TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
about
Genetic counseling for FTD/ALS caused by the C9ORF72 hexanucleotide expansionProgranulin in frontotemporal lobar degeneration and neuroinflammationDysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseasesPhosphorylation of microtubule-associated protein tau by AMPK-related kinasesTRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodiesVAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasisTDP-35 sequesters TDP-43 into cytoplasmic inclusions through binding with RNATARDBP mutation analysis in TDP-43 proteinopathies and deciphering the toxicity of mutant TDP-43C9ORF72, the new gene on the block, causes C9FTD/ALS: new insights provided by neuropathologyThe genetics and neuropathology of frontotemporal lobar degenerationALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear importA seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusionsThe pathobiology of splicingConjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUSAccumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer diseaseStructural insights into TDP-43 in nucleic-acid binding and domain interactionsA new subtype of frontotemporal lobar degeneration with FUS pathologyTDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicingFrom animal models to human disease: a genetic approach for personalized medicine in ALSInside out: the role of nucleocytoplasmic transport in ALS and FTLDMechanisms of FUS mutations in familial amyotrophic lateral sclerosisThe extreme N-terminus of TDP-43 mediates the cytoplasmic aggregation of TDP-43 and associated toxicity in vivoDysregulated axonal RNA translation in amyotrophic lateral sclerosisThe Use of Stem Cells to Model Amyotrophic Lateral Sclerosis and Frontotemporal Dementia: From Basic Research to Regenerative MedicineNeuroplasticity and Repair in Rodent Neurotoxic Models of Spinal Motoneuron DiseaseAlterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?New Insights into the Biological Role of Mammalian ADARs; the RNA Editing ProteinsPhenotypic Heterogeneity of Monogenic Frontotemporal DementiaUltrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesisModeling ALS and FTD with iPSC-derived neuronsMolecular motor proteins and amyotrophic lateral sclerosisMechanisms of granulin deficiency: lessons from cellular and animal modelsPathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disordersConverging mechanisms in ALS and FTD: disrupted RNA and protein homeostasisSumoylation of critical proteins in amyotrophic lateral sclerosis: emerging pathways of pathogenesisDoes a loss of TDP-43 function cause neurodegeneration?Redox regulation in amyotrophic lateral sclerosisALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formationInteraction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicityFunctional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosis
P2860
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P2860
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
TDP-43 is a component of ubiqu ...... amyotrophic lateral sclerosis
@ast
TDP-43 is a component of ubiqu ...... amyotrophic lateral sclerosis
@en
type
label
TDP-43 is a component of ubiqu ...... amyotrophic lateral sclerosis
@ast
TDP-43 is a component of ubiqu ...... amyotrophic lateral sclerosis
@en
prefLabel
TDP-43 is a component of ubiqu ...... amyotrophic lateral sclerosis
@ast
TDP-43 is a component of ubiqu ...... amyotrophic lateral sclerosis
@en
P2093
P3181
P1476
TDP-43 is a component of ubiqu ...... amyotrophic lateral sclerosis
@en
P2093
Hasegawa M
Hashizume Y
Tsuchiya K
P304
P3181
P356
10.1016/J.BBRC.2006.10.093
P407
P577
2006-12-22T00:00:00Z