Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
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Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's diseaseUbiquitin is phosphorylated by PINK1 to activate parkinPINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motilityMUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkinGenome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagyMitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagyShort mitochondrial ARF triggers Parkin/PINK1-dependent mitophagyPhosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neuronsThe role of oxidative stress in Parkinson's diseaseCytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagyThe Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagyHexokinase activity is required for recruitment of parkin to depolarized mitochondriaGenome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagyBroad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagyTransporting mitochondria in neuronsCross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and DiseaseAlterations in Mitochondrial Quality Control in Alzheimer's DiseaseParkin Regulation and Neurodegenerative DisordersAutophagy-Related Deubiquitinating Enzymes Involved in Health and DiseaseElectron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial BioenergeticsRBR E3 ubiquitin ligases: new structures, new insights, new questionsMitophagy in hematopoietic stem cells: the case for explorationParkin structure and functionMitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorderPoly (ADP-ribose) in the pathogenesis of Parkinson's diseaseThe pathways of mitophagy for quality control and clearance of mitochondriaMechanisms of mitochondria and autophagy crosstalkSelf and nonself: how autophagy targets mitochondria and bacteriaOxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cellsNear-infrared 808 nm light boosts complex IV-dependent respiration and rescues a Parkinson-related pink1 modelMitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration.Mechanisms of mitophagyPhosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tetheringPINK1-mediated phosphorylation of Parkin boosts Parkin activity in DrosophilaPINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrixDengue Virus Impairs Mitochondrial Fusion by Cleaving MitofusinsRole of autophagy in glycogen breakdown and its relevance to chloroquine myopathyThe yeast complex I equivalent NADH dehydrogenase rescues pink1 mutantsRole of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram SyndromeStructure of the human Parkin ligase domain in an autoinhibited state
P2860
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P248
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P2860
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Drosophila parkin requires PIN ...... on and ubiquitinates mitofusin
@ast
Drosophila parkin requires PIN ...... on and ubiquitinates mitofusin
@en
type
label
Drosophila parkin requires PIN ...... on and ubiquitinates mitofusin
@ast
Drosophila parkin requires PIN ...... on and ubiquitinates mitofusin
@en
prefLabel
Drosophila parkin requires PIN ...... on and ubiquitinates mitofusin
@ast
Drosophila parkin requires PIN ...... on and ubiquitinates mitofusin
@en
P2093
P2860
P921
P3181
P356
P1476
Drosophila parkin requires PIN ...... on and ubiquitinates mitofusin
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.0913485107
P407
P577
2010-03-16T00:00:00Z