Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner. - Wikidata - awgldk - TriplyDB

Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner.

Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner.

http://www.wikidata.org/entity/Q29616027

about

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation FAK promotes recruitment of talin to nascent adhesions to control cell motility Collagen remodeling by phagocytosis is determined by collagen substrate topology and calcium-dependent interactions of gelsolin with nonmuscle myosin IIA in cell adhesions The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration Myosins as fundamental components during tumorigenesis: diverse and indispensable Adhesion protein networks reveal functions proximal and distal to cell-matrix contacts Focal adhesions, stress fibers and mechanical tension Early events in cell spreading as a model for quantitative analysis of biomechanical events At the leading edge of three-dimensional cell migration The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration Mechanosensitivity and compositional dynamics of cell-matrix adhesions Changes in single-molecule integrin dynamics linked to local cellular behavior.The FAK-Arp2/3 interaction promotes leading edge advance and haptosensing by coupling nascent adhesions to lamellipodia actin.ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity.Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion.Protrusive waves guide 3D cell migration along nanofibers.Myosin II-mediated focal adhesion maturation is tension insensitive α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility Adhesive F-actin waves: a novel integrin-mediated adhesion complex coupled to ventral actin polymerization The focal adhesion-localized CdGAP regulates matrix rigidity sensing and durotaxis Breast cancer antiestrogen resistance 3 (BCAR3) promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells.Cell Invasion Dynamics into a Three Dimensional Extracellular Matrix Fibre Network Functional hierarchy of redundant actin assembly factors revealed by fine-grained registration of intrinsic image fluctuations.Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions.Arp2/3 inhibition induces amoeboid-like protrusions in MCF10A epithelial cells by reduced cytoskeletal-membrane coupling and focal adhesion assembly Myosin IIb activity and phosphorylation status determines dendritic spine and post-synaptic density morphology Dynamic modeling of cell migration and spreading behaviors on fibronectin coated planar substrates and micropatterned geometries Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration Nudel and FAK as antagonizing strength modulators of nascent adhesions through paxillin Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin ADVANCED IMAGING. Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics.Functions of nonmuscle myosin II in assembly of the cellular contractile system Computational estimates of membrane flow and tension gradient in motile cells The integrin-ligand interaction regulates adhesion and migration through a molecular clutch.Dynamin2 organizes lamellipodial actin networks to orchestrate lamellar actomyosin.Maturation of filopodia shaft adhesions is upregulated by local cycles of lamellipodia advancements and retractions From molecular signal activation to locomotion: an integrated, multiscale analysis of cell motility on defined matrices Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces Heading in the Right Direction: Understanding Cellular Orientation Responses to Complex Biophysical Environments

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P2860

Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner.

http://www.wikidata.org/entity/Q29616027

description

2008 nî lūn-bûn

@nan

2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Actin and alpha-actinin orches ...... n II motor-independent manner.

@ast

Actin and alpha-actinin orches ...... n II motor-independent manner.

@en

type

label

Actin and alpha-actinin orches ...... n II motor-independent manner.

@ast

Actin and alpha-actinin orches ...... n II motor-independent manner.

@en

prefLabel

Actin and alpha-actinin orches ...... n II motor-independent manner.

@ast

Actin and alpha-actinin orches ...... n II motor-independent manner.

@en

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Nature Cell Biology

P1476

Actin and alpha-actinin orches ...... n II motor-independent manner.

@en

P2093

Colin K Choi

http://www.w3.org/2001/XMLSchema#string

Jessica Zareno

http://www.w3.org/2001/XMLSchema#string

Leanna A Whitmore

http://www.w3.org/2001/XMLSchema#string

P2860

Conditional expression of a truncated fragment of nonmuscle myosin II-A alters cell shape but not cytokinesis in HeLa cells

Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis

Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C

Mutations in human nonmuscle myosin IIA found in patients with May-Hegglin anomaly and Fechtner syndrome result in impaired enzymatic function

Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion

Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.

Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia

P2888

P304

1039-1050

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scholarly article

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395093

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10.1038/NCB1763

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P433

9

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P478

10

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P50

Miguel Vicente-Manzanares

Alan Rick Horwitz

P577

2008-09-01T00:00:00Z

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23809066

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1052010823

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19160484

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2827253

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