The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses - Wikidata - awgldk - TriplyDB

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

http://www.wikidata.org/entity/Q29616349

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Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB OTULIN restricts Met1-linked ubiquitination to control innate immune signaling Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7 ATP-sensitive potassium channels mediate survival during infection in mammals and insects The A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7 Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1 Role of the A20-TRAF6 axis in lipopolysaccharide-mediated osteoclastogenesis LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activation The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1 Mitochondrially localised MUL1 is a novel modulator of antiviral signaling A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity Endotoxin tolerance impairs IL-1 receptor-associated kinase (IRAK) 4 and TGF-beta-activated kinase 1 activation, K63-linked polyubiquitination and assembly of IRAK1, TNF receptor-associated factor 6, and IkappaB kinase gamma and increases A20 expres Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling Immune responsive gene 1 (IRG1) promotes endotoxin tolerance by increasing A20 expression in macrophages through reactive oxygen species The gut flora as a forgotten organ Homeostasis and inflammation in the intestine Pathogen recognition and inflammatory signaling in innate immune defenses Function of Nod-like receptors in microbial recognition and host defense T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion.A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappaB activation Host nucleotide polymorphism in hepatitis B virus-associated hepatocellular carcinoma Roles of Autophagy and Autophagy-Related Proteins in Antifungal Immunity Potential association between TLR4 and chitinase 3-like 1 (CHI3L1/YKL-40) signaling on colonic epithelial cells in inflammatory bowel disease and colitis-associated cancer The role of ubiquitylation in immune defence and pathogen evasion Noncoding RNAs regulate NF-κB signaling to modulate blood vessel inflammation The genetic landscape of diffuse large B-cell lymphoma Deconstructing innate immune signaling in myelodysplastic syndromes Modulation of Intestinal TLR4-Inflammatory Signaling Pathways by Probiotic Microorganisms: Lessons Learned from Lactobacillus jensenii TL2937 Ubiquitin in the immune system Treg functional stability and its responsiveness to the microenvironment Dendritic cell-based immunotherapy for glioma: multiple regimens and implications in clinical trials TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy A20 (TNFAIP3) alleviates CVB3-induced myocarditis via inhibiting NF-κB signaling

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P2860

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

http://www.wikidata.org/entity/Q29616349

description

2004 nî lūn-bûn

@nan

2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

The ubiquitin-modifying enzyme ...... f Toll-like receptor responses

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The ubiquitin-modifying enzyme ...... f Toll-like receptor responses

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type

label

The ubiquitin-modifying enzyme ...... f Toll-like receptor responses

@ast

The ubiquitin-modifying enzyme ...... f Toll-like receptor responses

@en

prefLabel

The ubiquitin-modifying enzyme ...... f Toll-like receptor responses

@ast

The ubiquitin-modifying enzyme ...... f Toll-like receptor responses

@en

P1433

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P1433

Nature Immunology

P1476

The ubiquitin-modifying enzyme ...... f Toll-like receptor responses

@en

P2093

Averil Ma

http://www.w3.org/2001/XMLSchema#string

Cecile Pickart

http://www.w3.org/2001/XMLSchema#string

Colleen Tsui

http://www.w3.org/2001/XMLSchema#string

David L Boone

http://www.w3.org/2001/XMLSchema#string

Elizabeth McNally

http://www.w3.org/2001/XMLSchema#string

Eric G Lee

http://www.w3.org/2001/XMLSchema#string

Marcia Chien

http://www.w3.org/2001/XMLSchema#string

Matthew T Wheeler

http://www.w3.org/2001/XMLSchema#string

Osamu Hitotsumatsu

http://www.w3.org/2001/XMLSchema#string

Paula Hurley

http://www.w3.org/2001/XMLSchema#string

P2860

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

IRAK-M is a negative regulator of Toll-like receptor signaling

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling

Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity

Otubains: a new family of cysteine proteases in the ubiquitin pathway

The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

Toll-like receptors

Innate immune recognition

P304

1052-1060

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1688371

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NI1110

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

5

http://www.w3.org/2001/XMLSchema#string

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P577

2004-08-29T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

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8378469

http://www.w3.org/2001/XMLSchema#string

P698

15334086

http://www.w3.org/2001/XMLSchema#string

P921

Toll-like receptor