The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
about
Overexpression of the regulatory subunit of gamma-glutamylcysteine synthetase in HeLa cells increases gamma-glutamylcysteine synthetase activity and confers drug resistanceDiesel exhaust particle-induced alterations of pulmonary phase I and phase II enzymes of ratsHeme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibrosisThe glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulatorRegulation of the cardiac muscle ryanodine receptor by glutathione transferasesGene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localizationZeta, a novel class of glutathione transferases in a range of species from plants to humansMolecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductaseEvidence that human class Theta glutathione S-transferase T1-1 can catalyse the activation of dichloromethane, a liver and lung carcinogen in the mouse. Comparison of the tissue distribution of GST T1-1 with that of classes Alpha, Mu and Pi GST in hRationale for reclassification of a distinctive subdivision of mammalian class Mu glutathione S-transferases that are primarily expressed in testisThe distribution of theta-class glutathione S-transferases in the liver and lung of mouse, rat and humanBiochemical and genetic characterization of a murine class Kappa glutathione S-transferaseSubunit diversity and tissue distribution of human glutathione S-transferases: interpretations based on electrospray ionization-MS and peptide sequence-specific antiseraIdentification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4Structure and organization of the human theta-class glutathione S-transferase and D-dopachrome tautomerase gene complexGenomic organization, 5'-flanking region and chromosomal localization of the human glutathione transferase A4 geneMajor differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family membersModulation of the glutathione S-transferase in Ochrobactrum anthropi: function of xenobiotic substrates and other forms of stressMammalian class Sigma glutathione S-transferases: catalytic properties and tissue-specific expression of human and rat GSH-dependent prostaglandin D2 synthasesStructure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamilyGenome-wide transcription profile of field- and laboratory-selected dichlorodiphenyltrichloroethane (DDT)-resistant DrosophilaThe role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancerKeap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domainStructure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligaseComparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout miceNrf2 is a direct PERK substrate and effector of PERK-dependent cell survivalGlutathione transferases are structural and functional outliers in the thioredoxin foldGenes other than BRCA1 and BRCA2 involved in breast cancer susceptibilityFemales with paired occurrence of cancers in the UADT and genital region have a higher frequency of either Glutathione S-transferase M1/T1 null genotype.The Anopheles gambiae glutathione transferase supergene family: annotation, phylogeny and expression profilesCancer drug resistance: redox resetting renders a waymicroRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessmentGlutathione S-transferase M1 null genotype meta-analysis on gastric cancer riskGenetic susceptibility to lung cancer--light at the end of the tunnel?Pharmacogenomics of cisplatin sensitivity in non-small cell lung cancerEvolving concepts in cancer therapy through targeting sphingolipid metabolismCytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytesThe enhanced affinity for thiolate anion and activation of enzyme-bound glutathione is governed by an arginine residue of human Mu class glutathione S-transferasesIdentification, characterization, and crystal structure of the Omega class glutathione transferasesLocalization of the C-terminus of rat glutathione S-transferase A1-1: crystal structure of mutants W21F and W21F/F220Y
P2860
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P2860
The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
description
1995 nî lūn-bûn
@nan
1995 թուականին հրատարակուած գիտական յօդուած
@hyw
1995 թվականին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The glutathione S-transferase ...... protection and drug resistance
@ast
The glutathione S-transferase ...... protection and drug resistance
@en
type
label
The glutathione S-transferase ...... protection and drug resistance
@ast
The glutathione S-transferase ...... protection and drug resistance
@en
prefLabel
The glutathione S-transferase ...... protection and drug resistance
@ast
The glutathione S-transferase ...... protection and drug resistance
@en
P2860
P3181
P1476
The glutathione S-transferase ...... protection and drug resistance
@en
P2093
Pulford DJ
P2860
P304
P3181
P356
10.3109/10409239509083491
P407
P577
1995-01-01T00:00:00Z