Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
about
Rac and Rho GTPases in cancer cell motility controlMicroRNA-200 family members differentially regulate morphological plasticity and mode of melanoma cell invasionMYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasisRho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarityThe deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradationThe actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasionRegulatory domain selectivity in the cell-type specific PKN-dependence of cell migrationIdentification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damageThe Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbingCo-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasionPKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.Dynamic functions of RhoA in tumor cell migration and invasionOverexpression of CD99 Increases the Migration and Invasiveness of Human Malignant Glioma CellsRho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapyCell motility through plasma membrane blebbingMitf regulation of Dia1 controls melanoma proliferation and invasivenessRho, ROCK and actomyosin contractility in metastasis as drug targetsCell polarity signaling in the plasticity of cancer cell invasivenessRole of EMT in Metastasis and Therapy ResistanceNon-muscle myosin II in disease: mechanisms and therapeutic opportunitiesAt the leading edge of three-dimensional cell migrationFrom mechanical force to RhoA activationMatrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasionPhysical biology in cancer. 5. The rocky road of metastasis: the role of cytoskeletal mechanics in cell migratory response to 3D matrix topographyAssembly, heterogeneity, and breaching of the basement membranesWhy the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkersTumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkersA quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotypeA Novel Role of E-Cadherin-Based Adherens Junctions in Neoplastic Cell DisseminationMesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-βApolar and polar transitions drive the conversion between amoeboid and mesenchymal shapes in melanoma cells.Matrix-bound PAI-1 supports cell blebbing via RhoA/ROCK1 signalingTumor invasion optimization by mesenchymal-amoeboid heterogeneityUrothelial cells undergo epithelial-to-mesenchymal transition after exposure to muscle invasive bladder cancer exosomes.Cooperative anti-invasive effect of Cdc42/Rac1 activation and ROCK inhibition in SW620 colorectal cancer cells with elevated blebbing activityCompetition for actin between two distinct F-actin networks defines a bistable switch for cell polarization.Multiparametric classification links tumor microenvironments with tumor cell phenotypeThe RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin ContractilityReduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells
P2860
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P2860
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Differing modes of tumour cell ...... and extracellular proteolysis
@ast
Differing modes of tumour cell ...... and extracellular proteolysis
@en
type
label
Differing modes of tumour cell ...... and extracellular proteolysis
@ast
Differing modes of tumour cell ...... and extracellular proteolysis
@en
prefLabel
Differing modes of tumour cell ...... and extracellular proteolysis
@ast
Differing modes of tumour cell ...... and extracellular proteolysis
@en
P3181
P356
P1433
P1476
Differing modes of tumour cell ...... and extracellular proteolysis
@en
P2093
Christopher J Marshall
P2888
P304
P3181
P356
10.1038/NCB1019
P407
P50
P577
2003-08-01T00:00:00Z
P6179
1030299512