SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
about
Metabolism leaves its mark on the powerhouse: recent progress in post-translational modifications of lysine in mitochondriaSIRT2 as a Therapeutic Target for Age-Related Disordersp53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylaseGenetic variation in healthy oldest-oldSirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcriptionReversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stressCrystal structures of human SIRT3 displaying substrate-induced conformational changesSirtuins deacetylate and activate mammalian acetyl-CoA synthetasesGenetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE studyMultiple Aspects of Gene Dysregulation in Huntington's DiseaseSIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body productionSIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70Calorie restriction and the exercise of chromatinSIRT6 in DNA repair, metabolism and ageingSirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stressRole of ROS and RNS Sources in Physiological and Pathological ConditionsSirtuins and Cancer: Role in the Epithelial-Mesenchymal TransitionIn Search of New Therapeutic Targets in Obesity Treatment: SirtuinsReprogramming of energy metabolism as a driver of agingBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesRedox implications in adipose tissue (dys)function--A new look at old acquaintancesForever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegenerationSirtuin 1 and sirtuin 3: physiological modulators of metabolismRegulation of adipocyte autophagy--the potential anti-obesity mechanism of high density lipoprotein and ApolipoproteinA-ITargeting sirtuin 1 to improve metabolism: all you need is NAD(+)?NAD+ as a signaling molecule modulating metabolismSIRT3 as a Regulator of Non-alcoholic Fatty Liver DiseaseSIRT3 inhibits prostate cancer by destabilizing oncoprotein c-MYC through regulation of the PI3K/Akt pathway.Exercise-training in young Drosophila melanogaster reduces age-related decline in mobility and cardiac performanceECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs.Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: chemical and metabolic logic of acetyl-lysine modificationsBiotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4pNuclear export modulates the cytoplasmic Sir2 homologue Hst2.Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative diseaseHistone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancySIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgammaRedox regulation of mitochondrial functionOxidative stress and ROS metabolism via down-regulation of sirtuin 3 expression in Cmah-null mice affect hearing lossSIRT3 and cancer: tumor promoter or suppressor?
P2860
Q21129226-82075424-93FC-4FFE-8933-5276840EEE7AQ21129286-1A5BC305-9E72-49B7-9CBF-305C3C1BF77AQ21136386-60911737-6ABC-4AC7-B20E-7C735A45E31FQ21143740-CFB93B5E-110F-46F9-99F0-65D916C53FC0Q21296795-DA942793-F524-46D1-A620-DD0D21756175Q24294341-DE60C40A-7071-42C8-ACED-133FB77AC4C4Q24313709-5073A9D3-E1D4-4301-BF8A-DF90B6B8B9CFQ24338623-317E44CB-1782-455F-AB08-16357C02DE99Q24548362-D59B08A9-7BA0-4500-B17E-2C890EB31D78Q24600599-E5F5C920-4FF3-4C41-B789-9C22F040A328Q24605880-D15B5635-7B55-48D8-8DD1-C5F8A6FED92DQ24611702-476D9CE9-0705-42F4-8861-47D0A282FE3FQ24645120-EAA8CFFF-26A0-493C-A171-696CD7662813Q24652611-BBAFC352-6447-4AD6-8D05-C54ADA05878AQ24653962-E2501068-F9F1-4B2D-911E-E9F926BFC22CQ24670578-6196CB1C-B463-4E24-B2C8-B4847D1F6A8CQ26740342-1840F854-5484-498F-9CE2-D859CA7E0DE4Q26744502-F20B9FE5-5989-4164-91A6-CC3B8CC9CA1EQ26750982-5F96EA04-1114-4DC8-A956-2E16D8275F08Q26766053-7E75999B-866E-4064-A0EF-A1EED87851DBQ26777407-EFAED8B3-5945-4319-803E-A37CBF4D04FEQ26801347-B694D323-D830-4ABB-9CEF-33199F7CC4ACQ26825012-3D404843-63AE-4806-98C4-C3865B4CB3DBQ26828607-824C5833-0011-46EB-90B0-F8128B393A4FQ26859684-291555C5-88D6-4ACD-8526-3943CB90D474Q26864685-2A7F2ED1-A50A-4B0F-8281-7C57EA779CA0Q26995735-4FDC2F3F-5DCA-4349-8DBE-F3490027083BQ27009435-77A85CAB-A2B4-4538-8B30-59422239D45FQ27341759-FB6AC057-1116-4C21-9DF5-6CFB842A1A0FQ27348552-A3724A61-58B5-4F61-BD03-CD812C01490CQ27348871-E0017B79-9154-4B06-BEDC-41D6BAD8BED2Q27694582-78A612D3-498A-454A-A0A7-4D3D9F1A8790Q27930766-A8AE1E33-7168-4C00-8B4A-16138836FF29Q27934693-55D1EE64-A55F-41A4-98F9-34097D8BDF4BQ28068499-A94CF91F-2060-4C80-BD3B-E463A1AC0442Q28082536-CDB824D0-D585-4F51-8BFF-14315D4E8085Q28301961-19016C07-BFA3-48BD-95DF-D2A540A6E351Q28383361-C7634344-5612-4437-ADC6-4C10D91F5705Q28389690-15C11C00-2325-47EC-B334-0AD6270286B8Q28390097-2496D962-559C-4A87-8AD5-5890DB8152D4
P2860
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
description
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2005
@ast
im April 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 8 April 2005)
@en
wetenschappelijk artikel (gepubliceerd op 2005/04/08)
@nl
наукова стаття, опублікована у квітні 2005
@uk
مقالة علمية (نشرت في 8-4-2005)
@ar
name
SIRT3, a mitochondrial sirtuin ...... rmogenesis in brown adipocytes
@ast
SIRT3, a mitochondrial sirtuin ...... rmogenesis in brown adipocytes
@en
type
label
SIRT3, a mitochondrial sirtuin ...... rmogenesis in brown adipocytes
@ast
SIRT3, a mitochondrial sirtuin ...... rmogenesis in brown adipocytes
@en
prefLabel
SIRT3, a mitochondrial sirtuin ...... rmogenesis in brown adipocytes
@ast
SIRT3, a mitochondrial sirtuin ...... rmogenesis in brown adipocytes
@en
P2093
P3181
P356
P1476
SIRT3, a mitochondrial sirtuin ...... rmogenesis in brown adipocytes
@en
P2093
P304
P3181
P356
10.1074/JBC.M414670200
P407
P577
2005-04-08T00:00:00Z