4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway
about
Visualization of biochemical networks in living cellsInsulin receptor substrate-1 (IRS-1) forms a ribonucleoprotein complex associated with polysomesCCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNATranslational homeostasis via the mRNA cap-binding protein, eIF4ESignaling by target of rapamycin proteins in cell growth controlInsulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin.Fibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathwaysRegulation of mTOR and cell growth in response to energy stress by REDD1.Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damageMultiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repressionPhosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivoPhosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinasesRegulation of 4E-BP1 phosphorylation: a novel two-step mechanismSpatial regulation of the mTORC1 system in amino acids sensing pathwayCholesterol trafficking is required for mTOR activation in endothelial cellsThe tuberous sclerosis complexTargeting the mammalian target of rapamycin (mTOR): a new approach to treating cancerRheb and mTOR regulate neuronal polarity through Rap1BRegulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathwayPhylogenetic analysis of eIF4E-family membersOvercoming cisplatin resistance by mTOR inhibitor in lung cancer.Adapting the Stress Response: Viral Subversion of the mTOR Signaling PathwayOncogenes: The Passport for Viral Oncolysis Through PKR InhibitionKSHV-Mediated Angiogenesis in Tumor ProgressionCap-Independent Translational Control of CarcinogenesisThe organization and regulation of mRNA-protein complexesSignalling to eIF4E in cancerCutting through the complexities of mTOR for the treatment of strokeFOXO transcription factors throughout T cell biologyPhosphatidylinositol 3-kinase and antiestrogen resistance in breast cancerShedding new light on neurodegenerative diseases through the mammalian target of rapamycinThe regulation of the autophagic network and its implications for human diseaseStatus of PI3K/Akt/mTOR pathway inhibitors in lymphomaRole of glucose metabolism and ATP in maintaining PINK1 levels during Parkin-mediated mitochondrial damage responses.The Translational Repressor 4E-BP1 Contributes to Diabetes-Induced Visual DysfunctionEnhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenicPosttranscriptional control of gene expression in yeast.
P2860
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P2860
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
4E-BP1, a repressor of mRNA tr ...... the Akt(PKB) signaling pathway
@ast
4E-BP1, a repressor of mRNA tr ...... the Akt(PKB) signaling pathway
@en
type
label
4E-BP1, a repressor of mRNA tr ...... the Akt(PKB) signaling pathway
@ast
4E-BP1, a repressor of mRNA tr ...... the Akt(PKB) signaling pathway
@en
prefLabel
4E-BP1, a repressor of mRNA tr ...... the Akt(PKB) signaling pathway
@ast
4E-BP1, a repressor of mRNA tr ...... the Akt(PKB) signaling pathway
@en
P2093
P2860
P3181
P356
P1433
P1476
4E-BP1, a repressor of mRNA tr ...... the Akt(PKB) signaling pathway
@en
P2093
P2860
P304
P3181
P356
10.1101/GAD.12.4.502
P407
P577
1998-02-01T00:00:00Z