Hierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation.
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Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiaeAn N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing.Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycleHuman geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosisThe replication fork: understanding the eukaryotic replication machinery and the challenges to genome duplicationHow do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexesCDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 proteinGenomic instability in cancer.Dual role of the Cdc7-regulatory protein Dbf4 during yeast meiosis.The mcm5-bob1 bypass of Cdc7p/Dbf4p in DNA replication depends on both Cdk1-independent and Cdk1-dependent steps in Saccharomyces cerevisiae.Ordered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins.Early expressed Clb proteins allow accumulation of mitotic cyclin by inactivating proteolytic machinery during S phaseHuman Dbf4/ASK promoter is activated through the Sp1 and MluI cell-cycle box (MCB) transcription elementsA 63-base pair DNA segment containing an Sp1 site but not a canonical E2F site can confer growth-dependent and E2F-mediated transcriptional stimulation of the human ASK gene encoding the regulatory subunit for human Cdc7-related kinaseIdentification of Mcm2 phosphorylation sites by S-phase-regulating kinasesMathematical modelling of DNA replication reveals a trade-off between coherence of origin activation and robustness against rereplicationDbf4-Cdc7 phosphorylation of Mcm2 is required for cell growth.Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeastEukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases.CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor I with chromatin.Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex.Universal temporal profile of replication origin activation in eukaryotesInteraction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch.Degradation or maintenance: actions of the ubiquitin system on eukaryotic chromatinCdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progressionThe Cdc7/Dbf4 protein kinase: target of the S phase checkpoint?A conserved domain of Schizosaccharomyces pombe dfp1(+) is uniquely required for chromosome stability following alkylation damage during S phasePhosphorylated Rad18 directs DNA polymerase η to sites of stalled replicationCdc7 kinase complex: a key regulator in the initiation of DNA replication.A Dbf4p BRCA1 C-terminal-like domain required for the response to replication fork arrest in budding yeast.The effective application of a discrete transition model to explore cell-cycle regulation in yeast.The Cdc45·Mcm2-7·GINS protein complex in trypanosomes regulates DNA replication and interacts with two Orc1-like proteins in the origin recognition complex.Eukaryotic MCM proteins: beyond replication initiation.Mutations in Replicative Stress Response Pathways Are Associated with S Phase-specific Defects in Nucleotide Excision RepairStructural changes in Mcm5 protein bypass Cdc7-Dbf4 function and reduce replication origin efficiency in Saccharomyces cerevisiae.Interplay between S-cyclin-dependent kinase and Dbf4-dependent kinase in controlling DNA replication through phosphorylation of yeast Mcm4 N-terminal domainCell cycle regulation of DNA replication.The Hsk1(Cdc7) replication kinase regulates origin efficiencyIncorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation
P2860
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P2860
Hierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation.
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
Hierarchy of S-phase-promoting ...... n-dependent kinase activation.
@ast
Hierarchy of S-phase-promoting ...... n-dependent kinase activation.
@en
type
label
Hierarchy of S-phase-promoting ...... n-dependent kinase activation.
@ast
Hierarchy of S-phase-promoting ...... n-dependent kinase activation.
@en
prefLabel
Hierarchy of S-phase-promoting ...... n-dependent kinase activation.
@ast
Hierarchy of S-phase-promoting ...... n-dependent kinase activation.
@en
P2093
P2860
P1476
Hierarchy of S-phase-promoting ...... n-dependent kinase activation.
@en
P2093
Della Seta F
Nougarède R
P2860
P304
P356
10.1128/MCB.20.11.3795-3806.2000
P407
P577
2000-06-01T00:00:00Z