Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels
about
Large-scale analysis of conserved rare codon clusters suggests an involvement in co-translational molecular recognition eventsProtein functional features are reflected in the patterns of mRNA translation speed.Entrainment to periodic initiation and transition rates in a computational model for gene translationFrequent GU wobble pairings reduce translation efficiency in Plasmodium falciparumWidespread position-specific conservation of synonymous rare codons within coding sequences.Quantifying position-dependent codon usage bias.The effect of tRNA levels on decoding times of mRNA codons.Modelling the efficiency of codon-tRNA interactions based on codon usage bias.tRNAs: new tricks from old dogs.Probing the limits of genetic recoding in essential genes.Determinants of translation elongation speed and ribosomal profiling biases in mouse embryonic stem cells.Ribosome traffic on mRNAs maps to gene ontology: genome-wide quantification of translation initiation rates and polysome size regulation.Positively charged residues are the major determinants of ribosomal velocityGenetic code-guided protein synthesis and folding in Escherichia coli.A condition-specific codon optimization approach for improved heterologous gene expression in Saccharomyces cerevisiae.Unraveling patterns of site-to-site synonymous rates variation and associated gene properties of protein domains and families.Next-generation sequencing of flow-sorted wheat chromosome 5D reveals lineage-specific translocations and widespread gene duplicationsProperties and determinants of codon decoding time distributions.Uncovering Hidden Layers of Cell Cycle Regulation through Integrative Multi-omic AnalysisGenome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human CellsPrevalent Accumulation of Non-Optimal Codons through Somatic Mutations in Human Cancers.Codon Bias as a Means to Fine-Tune Gene Expression.A model for competition for ribosomes in the cellMeasurement and modeling of transcriptional noise in the cell cycle regulatory network.Predictive biophysical modeling and understanding of the dynamics of mRNA translation and its evolution.Translate to divide: control of the cell cycle by protein synthesis.The Code of Silence: Widespread Associations Between Synonymous Codon Biases and Gene Function.Codon Optimization Leads to Functional Impairment of RD114-TR Envelope Glycoprotein.When mRNA translation meets decay.Hepatitis A virus adaptation to cellular shutoff is driven by dynamic adjustments of codon usage and results in the selection of populations with altered capsids.Improving virus production through quasispecies genomic selection and molecular breeding.Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitnessCoevolution mechanisms that adapt viruses to genetic code variations implemented in their hosts.Predicting synonymous codon usage and optimizing the heterologous gene for expression in E. coli.Transcriptome-wide analysis of the Trypanosoma cruzi proliferative cycle identifies the periodically expressed mRNAs and their multiple levels of control.Codon bias among synonymous rare variants is associated with Alzheimer's disease imaging biomarker.A code for transcription elongation speed.A novel framework for evaluating the performance of codon usage bias metrics.Computational analysis of the oscillatory behavior at the translation level induced by mRNA levels oscillations due to finite intracellular resources.Cells alter their tRNA abundance to selectively regulate protein synthesis during stress conditions
P2860
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P2860
Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Genes adopt non-optimal codon ...... oscillations in protein levels
@ast
Genes adopt non-optimal codon ...... oscillations in protein levels
@en
type
label
Genes adopt non-optimal codon ...... oscillations in protein levels
@ast
Genes adopt non-optimal codon ...... oscillations in protein levels
@en
prefLabel
Genes adopt non-optimal codon ...... oscillations in protein levels
@ast
Genes adopt non-optimal codon ...... oscillations in protein levels
@en
P2093
P2860
P50
P3181
P356
P1476
Genes adopt non-optimal codon ...... oscillations in protein levels
@en
P2093
Lydia Cohen
Takao Igarashi
Tamar Danon
Thomas Christian
P2860
P3181
P356
10.1038/MSB.2012.3
P577
2012-02-28T00:00:00Z