AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders. - Wikidata - awgldk - TriplyDB

AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders.

AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders.

http://www.wikidata.org/entity/Q30010179

about

Non-manifesting AHI1 truncations indicate localized loss-of-function tolerance in a severe Mendelian disease gene Targeting primitive chronic myeloid leukemia cells by effective inhibition of a new AHI-1-BCR-ABL-JAK2 complex.Selective JAK2/ABL dual inhibition therapy effectively eliminates TKI-insensitive CML stem/progenitor cells.Primary cilia proteins: ciliary and extraciliary sites and functions.MS AHI1 genetic risk promotes IFNγ+ CD4+ T cells.The multiple sclerosis risk allele within the AHI1 gene is associated with relapses in children and adults.BIN1 tumor suppressor regulates Fas/Fas ligand-mediated apoptosis through c-FLIP in cutaneous T-cell lymphoma.Gene expression imputation identifies candidate genes and susceptibility loci associated with cutaneous squamous cell carcinoma

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P2860

AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders.

http://www.wikidata.org/entity/Q30010179

description

2011 nî lūn-bûn

@nan

2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

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name

AHI-1: a novel signaling prote ...... leukemia and brain disorders.

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AHI-1: a novel signaling prote ...... leukemia and brain disorders.

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type

label

AHI-1: a novel signaling prote ...... leukemia and brain disorders.

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AHI-1: a novel signaling prote ...... leukemia and brain disorders.

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prefLabel

AHI-1: a novel signaling prote ...... leukemia and brain disorders.

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AHI-1: a novel signaling prote ...... leukemia and brain disorders.

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AHI-1: a novel signaling prote ...... leukemia and brain disorders.

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Sharmin Esmailzadeh

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Xiaoyan Jiang

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Creative Commons Attribution 2.5 Unported

P2860

Deregulated expression in Ph+ human leukemias of AHI-1, a gene activated by insertional mutagenesis in mouse models of leukemia

A huntingtin-associated protein enriched in brain with implications for pathology

A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants

BIN1 is a novel MYC-interacting protein with features of a tumour suppressor

Description, nomenclature, and mapping of a novel cerebello-renal syndrome with the molar tooth malformation.

A role for the putative tumor suppressor Bin1 in muscle cell differentiation

Mutations in the AHI1 gene, encoding jouberin, cause Joubert syndrome with cortical polymicrogyria.

Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrations

Wnt/beta-catenin signaling: components, mechanisms, and diseases

The amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulation

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918-934

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scholarly article

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10.18632/ONCOTARGET.405

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12

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transport protein

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3282096

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