Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
about
Podoplanin - a small glycoprotein with many facesPodoplanin: emerging functions in development, the immune system, and cancerThe CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.Podoplanin associates with CD44 to promote directional cell migrationPodoplanin-Fc reduces lymphatic vessel formation in vitro and in vivo and causes disseminated intravascular coagulation when transgenically expressed in the skinMutation of threonine 34 in mouse podoplanin-Fc reduces CLEC-2 binding and toxicity in vivo while retaining antilymphangiogenic activity.Role of galectins in re-epithelialization of wounds.Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins.Development of the endothelium: an emphasis on heterogeneityPKA and CDK5 can phosphorylate specific serines on the intracellular domain of podoplanin (PDPN) to inhibit cell motilityGalectin-1 regulates tissue exit of specific dendritic cell populations.Plant lectin can target receptors containing sialic acid, exemplified by podoplanin, to inhibit transformed cell growth and migration.Binding of Hyaluronan to the Native Lymphatic Vessel Endothelial Receptor LYVE-1 Is Critically Dependent on Receptor Clustering and Hyaluronan OrganizationPathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3.A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interactionThe road less traveled: regulation of leukocyte migration across vascular and lymphatic endothelium by galectins.Novel platelet activation receptor CLEC-2: from discovery to prospects.Gene expression profile of lymphatic endothelial cells.The impact of Aggrus/podoplanin on platelet aggregation and tumour metastasis.Galectin-8: a matricellular lectin with key roles in angiogenesis.Galectins in tumor angiogenesisPlatelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse.Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms.Podoplanin negatively regulates CD4+ effector T cell responses.
P2860
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P2860
Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
@ast
Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
@en
type
label
Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
@ast
Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
@en
prefLabel
Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
@ast
Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
@en
P2860
P921
P3181
P1476
Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
@en
P2093
Leah N Cueni
P2860
P304
P3181
P356
10.1016/J.YEXCR.2009.02.021
P407
P577
2009-03-04T00:00:00Z