about
TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activityShadoo/PrP (Sprn(0/0) /Prnp(0/0) ) double knockout mice: more than zeroesEvolutionary descent of prion genes from the ZIP family of metal ion transportersInteractome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperonesAbeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathologyLysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutationsThe PrP-like protein Doppel binds copperThe in vivo brain interactome of the amyloid precursor proteinKnockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrP(C)-deficiencyPresenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brainThe prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
David Westaway
@ast
David Westaway
@en
David Westaway
@es
David Westaway
@nl
David Westaway
@sl
type
label
David Westaway
@ast
David Westaway
@en
David Westaway
@es
David Westaway
@nl
David Westaway
@sl
prefLabel
David Westaway
@ast
David Westaway
@en
David Westaway
@es
David Westaway
@nl
David Westaway
@sl