Alternative binding proteins: anticalins - harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding activities.
about
High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromonesNon-antibody protein-based biosensorsStructure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolismNMR Structure and Dynamics of the Engineered Fluorescein-Binding Lipocalin FluA Reveal Rigidification of β-Barrel and Variable Loops upon Enthalpy-Driven Ligand BindingStructural analysis ofBacillus pumilusphenolic acid decarboxylase, a lipocalin-fold enzymeTwo modes of fatty acid binding to bovine β-lactoglobulin--crystallographic and spectroscopic studiesStructure and ligand-binding properties of the biogenic amine-binding protein from the saliva of a blood-feeding insect vector ofTrypanosoma cruziThe differences in binding 12-carbon aliphatic ligands by bovine β-lactoglobulin isoform A and B studied by isothermal titration calorimetry and X-ray crystallographyStructure and Mechanism of the Phycobiliprotein Lyase CpcTMechanisms of action of therapeutic antibodies for cancerAn albumin-derived peptide scaffold capable of binding and catalysisThe coat morphogenetic protein SpoVID is necessary for spore encasement in Bacillus subtilisThe quaternary structure of the recombinant bovine odorant-binding protein is modulated by chemical denaturantsAll-Purpose Containers? Lipid-Binding Protein - Drug InteractionsEngineered β-Lactoglobulin Produced in E. coli: Purification, Biophysical and Structural CharacterisationDirected Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase.Isolation of monobodies that bind specifically to the SH3 domain of the Fyn tyrosine protein kinase.Bovine beta-lactoglobulin acts as an acid-resistant drug carrier by exploiting its diverse binding regions.Practical tips for construction of custom Peptide libraries and affinity selection by using commercially available phage display cloning systemsLipocalinPred: a SVM-based method for prediction of lipocalins.Creating novel proteins by combining design and selectionMultimodality multiparametric imaging of early tumor response to a novel antiangiogenic therapy based on anticalins.Cyclotides, a promising molecular scaffold for peptide-based therapeutics.Cystine-knot peptides engineered with specificities for α(IIb)β(3) or α(IIb)β(3) and α(v)β(3) integrins are potent inhibitors of platelet aggregation.Drop-out phagemid vector for switching from phage displayed affinity reagents to expression formatsBacterial display in combinatorial protein engineering.Peptide aptamers: development and applications.Improving the pharmacokinetic properties of biologics by fusion to an anti-HSA shark VNAR domainDevelopment of a new positron emission tomography tracer for targeting tumor angiogenesis: synthesis, small animal imaging, and radiation dosimetry.Nanobody mediated crystallization of an archeal mechanosensitive channel.Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step.Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library.Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.Iron deficiency or anemia of inflammation? : Differential diagnosis and mechanisms of anemia of inflammationSample preparation: the forgotten beginning.Detection of pathogens in foods: the current state-of-the-art and future directions.Nucleic acid and peptide aptamers: fundamentals and bioanalytical aspects.RECRUIT-TandAbs: harnessing the immune system to kill cancer cells.Manipulation of the hepcidin pathway for therapeutic purposes.Antibody mimetics: promising complementary agents to animal-sourced antibodies.
P2860
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P2860
Alternative binding proteins: anticalins - harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding activities.
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Alternative binding proteins: ...... neer novel binding activities.
@ast
Alternative binding proteins: ...... neer novel binding activities.
@en
type
label
Alternative binding proteins: ...... neer novel binding activities.
@ast
Alternative binding proteins: ...... neer novel binding activities.
@en
prefLabel
Alternative binding proteins: ...... neer novel binding activities.
@ast
Alternative binding proteins: ...... neer novel binding activities.
@en
P2860
P1433
P1476
Alternative binding proteins: ...... neer novel binding activities.
@en
P2860
P304
P356
10.1111/J.1742-4658.2008.06439.X
P407
P50
P577
2008-04-24T00:00:00Z