Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness. - Wikidata - awgldk - TriplyDB

Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.

Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.

http://www.wikidata.org/entity/Q30160185

about

Ubiquitylation-dependent downregulation of Nck regulates its functional activity ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover Paxillin comes of age FAK and paxillin, two potential targets in pancreatic cancer GIT2 acts as a potential keystone protein in functional hypothalamic networks associated with age-related phenotypic changes in rats LIM domains target actin regulators paxillin and zyxin to sites of stress fiber strain Monitoring the cytoskeletal EGF response in live gastric carcinoma cells The multifunctional GIT family of proteins Role played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier function Extracellular signal-regulated kinase activation during renal ischemia/reperfusion mediates focal adhesion dissolution and renal injury Nck adapter proteins: functional versatility in T cells The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.The mTOR-FAK mechanotransduction signaling axis for focal adhesion maturation and cell proliferation.Integrins in cell migration Adhesion dynamics at a glance.Regulation of actin cytoskeleton dynamics by Arf-family GTPases.Paxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration.Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX.Impaired fear response in mice lacking GIT1.Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.The cell adhesion-associated protein Git2 regulates morphogenetic movements during zebrafish embryonic development.Phosphorylation of the cool-1/beta-Pix protein serves as a regulatory signal for the migration and invasive activity of Src-transformed cells.Connective Tissue Growth Factor (CTGF/CCN2) enhances lactogenic differentiation of mammary epithelial cells via integrin-mediated cell adhesion Biglycan enhances gastric cancer invasion by activating FAK signaling pathway Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells Focal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasis Association of FAK activation with lentivirus-induced disruption of blood-brain barrier tight junction-associated ZO-1 protein organization Maspin regulates endothelial cell adhesion and migration through an integrin signaling pathway.Emerging role of paxillin-PKL in regulation of cell adhesion, polarity and migration Focal adhesions in osteoneogenesis Mechanical integration of actin and adhesion dynamics in cell migration.Short term exposure of beta cells to low concentrations of interleukin-1β improves insulin secretion through focal adhesion and actin remodeling and regulation of gene expression.Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis.c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury ERp19 contributes to tumorigenicity in human gastric cancer by promoting cell growth, migration and invasion.SHP-2 Mediates Cryptosporidium parvum Infectivity in Human Intestinal Epithelial Cells.Expression of Paxillin is Correlated with Clinical Prognosis in Colorectal Cancer Patients GIT2 deficiency attenuates concanavalin A-induced hepatitis in mice

P2860

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P2860

Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.

http://www.wikidata.org/entity/Q30160185

description

2005 nî lūn-bûn

@nan

2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Src and FAK kinases cooperate ...... spreading and protrusiveness.

@ast

Src and FAK kinases cooperate ...... spreading and protrusiveness.

@en

type

label

Src and FAK kinases cooperate ...... spreading and protrusiveness.

@ast

Src and FAK kinases cooperate ...... spreading and protrusiveness.

@en

prefLabel

Src and FAK kinases cooperate ...... spreading and protrusiveness.

@ast

Src and FAK kinases cooperate ...... spreading and protrusiveness.

@en

P1433

Q30160185-40A4F0E6-9246-4EFC-A01D-57B21AA98099

P1476

Q30160185-F2396B14-8E6A-4C91-A689-48136DD45293

P2093

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P2860

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P31

Q30160185-B64FB331-4383-4571-8E2D-D8784E672E59

P356

Q30160185-23166915-FC75-409C-A30F-188AF9E8AF92

P433

Q30160185-C9AC58B9-E38D-4775-A1DB-10063DCD7305

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Q30160185-44D5D317-50EE-48BA-9007-4D1748D435A7

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P932

Q30160185-002EF074-A489-4171-9E85-5FE53524C8F2

P356

MBC.E05-02-0131

P1433

Molecular Biology of the Cell

P1476

Src and FAK kinases cooperate ...... spreading and protrusiveness.

@en

P2093

Christopher E Turner

http://www.w3.org/2001/XMLSchema#string

Jennifer S Jamieson

http://www.w3.org/2001/XMLSchema#string

Jonathan A Cooper

http://www.w3.org/2001/XMLSchema#string

Leslie A Cary

http://www.w3.org/2001/XMLSchema#string

Michael C Brown

http://www.w3.org/2001/XMLSchema#string

P2860

ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.

The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing

Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton

Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway

Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly

P304

4316-4328

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P31

scholarly article

P356

10.1091/MBC.E05-02-0131

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P433

9

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P478

16

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P577

2005-07-06T00:00:00Z

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P698

16000375

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P921

phosphorylation

P932

1196340

http://www.w3.org/2001/XMLSchema#string