Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II.
about
Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling.Structural basis for regulation of the Crk signaling protein by a proline switch.Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substratePhosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivationThe carboxyl-terminal SH3 domain of the mammalian adaptor CrkII promotes internalization of Listeria monocytogenes through activation of host phosphoinositide 3-kinase.Proline cis-trans isomerization controls autoinhibition of a signaling protein.Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3 domain.Host adaptor proteins Gab1 and CrkII promote InlB-dependent entry of Listeria monocytogenes.v-Crk activates the phosphoinositide 3-kinase/AKT pathway by utilizing focal adhesion kinase and H-Ras.Tuning protein autoinhibition by domain destabilizationPhosphorylation of RACK1 on tyrosine 52 by c-Abl is required for insulin-like growth factor I-mediated regulation of focal adhesion kinase.Role of c-Abl in directing metabolic versus mitogenic effects in insulin receptor signaling.Crk and CrkL adaptor proteins: networks for physiological and pathological signaling
P2860
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P2860
Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Activation of the focal adhesi ...... l-terminal region of c-Crk II.
@ast
Activation of the focal adhesi ...... l-terminal region of c-Crk II.
@en
type
label
Activation of the focal adhesi ...... l-terminal region of c-Crk II.
@ast
Activation of the focal adhesi ...... l-terminal region of c-Crk II.
@en
prefLabel
Activation of the focal adhesi ...... l-terminal region of c-Crk II.
@ast
Activation of the focal adhesi ...... l-terminal region of c-Crk II.
@en
P2093
P2860
P356
P1433
P1476
Activation of the focal adhesi ...... l-terminal region of c-Crk II.
@en
P2093
Escalante M
Fajardo JE
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204173
P407
P577
2001-02-01T00:00:00Z
P5875
P6179
1045538994