Differential interactions of the growth factor receptor-bound protein 2 N-SH3 domain with son of sevenless and dynamin. Potential role in the Ras-dependent signaling pathway.
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Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein)A novel proteomic screen for peptide-protein interactionsSH3 domains of Grb2 adaptor bind to PXpsiPXR motifs within the Sos1 nucleotide exchange factor in a discriminate mannerBivalent binding drives the formation of the Grb2-Gab1 signaling complex in a noncooperative mannerStimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteinsEffect of pH and salt bridges on structural assembly: Molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domainTGF-β2 induces Grb2 to recruit PI3-K to TGF-RII that activates JNK/AP-1-signaling and augments invasiveness of Theileria-transformed macrophages.Regions outside of conserved PxxPxR motifs drive the high affinity interaction of GRB2 with SH3 domain ligandsMolecular cloning and characterization of growth factor receptor bound-protein in Clonorchis sinensis.Allostery mediates ligand binding to Grb2 adaptor in a mutually exclusive manner.Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pitsKinetics of Src homology 3 domain association with the proline-rich domain of dynamins: specificity, occlusion, and the effects of phosphorylation.Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre.Grb2 dominantly associates with dynamin II in human hepatocellular carcinoma HepG2 cells.The design of a hyperstable mutant of the Abp1p SH3 domain by sequence alignment analysisAssembly of the Sos1-Grb2-Gab1 ternary signaling complex is under allosteric controlBinding of the cSH3 domain of Grb2 adaptor to two distinct RXXK motifs within Gab1 docker employs differential mechanisms.Transmembrane adapters: attractants for cytoplasmic effectors.High affinity molecules disrupting GRB2 protein complexes as a therapeutic strategy for chronic myelogenous leukaemia.Multivalent binding and facilitated diffusion account for the formation of the Grb2-Sos1 signaling complex in a cooperative manner.Requirement of receptor internalization for opioid stimulation of mitogen-activated protein kinase: biochemical and immunofluorescence confocal microscopic evidenceCell penetrating peptides to dissect host-pathogen protein-protein interactions in Theileria-transformed leukocytes.
P2860
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P2860
Differential interactions of the growth factor receptor-bound protein 2 N-SH3 domain with son of sevenless and dynamin. Potential role in the Ras-dependent signaling pathway.
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Differential interactions of t ...... s-dependent signaling pathway.
@ast
Differential interactions of t ...... s-dependent signaling pathway.
@en
type
label
Differential interactions of t ...... s-dependent signaling pathway.
@ast
Differential interactions of t ...... s-dependent signaling pathway.
@en
prefLabel
Differential interactions of t ...... s-dependent signaling pathway.
@ast
Differential interactions of t ...... s-dependent signaling pathway.
@en
P2093
P2860
P356
P1476
Differential interactions of t ...... s-dependent signaling pathway.
@en
P2093
Cornille F
Duchesne M
Montiel JL
P2860
P304
P356
10.1074/JBC.273.9.5343
P407
P577
1998-02-01T00:00:00Z