Interactions between the cytosolic components p47phox and p67phox of the human neutrophil NADPH oxidase that are not required for activation in the cell-free system.
about
A fluorescently tagged C-terminal fragment of p47phox detects NADPH oxidase dynamics during phagocytosis.Effects of p47phox C terminus phosphorylations on binding interactions with p40phox and p67phox. Structural and functional comparison of p40phox and p67phox SH3 domainsMechanisms of NADPH oxidase activation: translocation of p40phox, Rac1 and Rac2 from the cytosol to the membranes in human neutrophils lacking p47phox or p67phoxDirect interaction between FcgammaRI (CD64) and periplakin controls receptor endocytosis and ligand binding capacityThe 40-kDa component of the phagocyte NADPH oxidase (p40phox) is phosphorylated during activation in differentiated HL60 cellsStructure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen speciesp40(phox) down-regulates NADPH oxidase activity through interactions with its SH3 domainThe adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase.Activation of the phagocyte NADPH oxidase protein p47(phox). Phosphorylation controls SH3 domain-dependent binding to p22(phox).Mapping of functional domains in p47(phox) involved in the activation of NADPH oxidase by "peptide walking".Specificity of p47phox SH3 domain interactions in NADPH oxidase assembly and activation.Assembly and activation of the phagocyte NADPH oxidase. Specific interaction of the N-terminal Src homology 3 domain of p47phox with p22phox is required for activation of the NADPH oxidase.Interactions between cytosolic components of the NADPH oxidase: p40phox interacts with both p67phox and p47phox.Assembly of the human neutrophil NADPH oxidase involves binding of p67phox and flavocytochrome b to a common functional domain in p47phox.An SH3 domain-mediated interaction between the phagocyte NADPH oxidase factors p40phox and p47phox.Multiple SH3 domain interactions regulate NADPH oxidase assembly in whole cells.The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators.Molecular evolution of Phox-related regulatory subunits for NADPH oxidase enzymes.A conserved region between the TPR and activation domains of p67phox participates in activation of the phagocyte NADPH oxidase.Platelet-activating factor-mediated endosome formation causes membrane translocation of p67phox and p40phox that requires recruitment and activation of p38 MAPK, Rab5a, and phosphatidylinositol 3-kinase in human neutrophils.Functional pseudogenes inhibit the superoxide production.The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems.The NOX toolbox: validating the role of NADPH oxidases in physiology and disease.Disturbed interaction of p21-rac with mutated p67-phox causes chronic granulomatous diseaseInsights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease.Nox2 contributes to hyperinsulinemia-induced redox imbalance and impaired vascular function.The major phosphorylation site of the NADPH oxidase component p67phox is Thr233.De novo ICAM-1 synthesis in the mouse lung: model of assessment of protein expression in lungs.Stimulators of AMP-activated protein kinase inhibit the respiratory burst in human neutrophils.Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1.
P2860
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P2860
Interactions between the cytosolic components p47phox and p67phox of the human neutrophil NADPH oxidase that are not required for activation in the cell-free system.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Interactions between the cytos ...... ation in the cell-free system.
@ast
Interactions between the cytos ...... ation in the cell-free system.
@en
type
label
Interactions between the cytos ...... ation in the cell-free system.
@ast
Interactions between the cytos ...... ation in the cell-free system.
@en
prefLabel
Interactions between the cytos ...... ation in the cell-free system.
@ast
Interactions between the cytos ...... ation in the cell-free system.
@en
P2093
P356
P1476
Interactions between the cytos ...... vation in the cell-free system
@en
P2093
A J Verhoeven
B G Bolscher
P M Hilarius
P304
11216-11221
P356
10.1074/JBC.270.19.11216
P407
P577
1995-05-01T00:00:00Z