Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes.
about
hSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathwaysProtein-tyrosine kinase Pyk2 is involved in interleukin-2 production by Jurkat T cells via its tyrosine 402Identification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase Cgamma, Grb2, and Vav after B cell antigen receptor activationSocs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferationVav family proteins couple to diverse cell surface receptorsRegulatory and signaling properties of the Vav familyInteraction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expressionAnalysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptorsp95vav associates with the nuclear protein Ku-70Vav2 is required for cell spreadingVav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activationRho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseaseRgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrinsT-cell receptor- and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue.Two Closely Spaced Tyrosines Regulate NFAT Signaling in B Cells via Syk Association with VavVav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyteVav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathwaysInteractions between the protein-tyrosine kinase ZAP-70, the proto-oncoprotein Vav, and tubulin in Jurkat T cellsT cell activation through the CD43 molecule leads to Vav tyrosine phosphorylation and mitogen-activated protein kinase pathway activationSignal transduction by CD28 costimulatory receptor on T cells. B7-1 and B7-2 regulation of tyrosine kinase adaptor moleculesSos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptorsTyrosine 474 of ZAP-70 is required for association with the Shc adaptor and for T-cell antigen receptor-dependent gene activationDifferential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphataseThe adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteriaSignaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphataseNuclear-cytoplasmic shuttling of C-ABL tyrosine kinaseTyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcriptionFyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cellsVav in natural killer cells is tyrosine phosphorylated upon cross-linking of Fc gamma RIIIA and is constitutively associated with a serine/threonine kinaseStructural determinants for the biological activity of Vav proteins.Vav1 is a component of transcriptionally active complexes.Identification of the Drosophila melanogaster homologue of the mammalian signal transducer protein, Vav.p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cellsExpression of a Chimeric Antigen Receptor in Multiple Leukocyte Lineages in Transgenic MiceA Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNKVav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activityThe chromosomal duplication model of the major histocompatibility complex.Signal transduction in T lymphocytes using a conditional allele of SosThe GTPase Rho has a critical regulatory role in thymus development.Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B.
P2860
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P2860
Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Defective T-cell receptor sign ...... eficient CD4+ CD8+ thymocytes.
@ast
Defective T-cell receptor sign ...... eficient CD4+ CD8+ thymocytes.
@en
type
label
Defective T-cell receptor sign ...... eficient CD4+ CD8+ thymocytes.
@ast
Defective T-cell receptor sign ...... eficient CD4+ CD8+ thymocytes.
@en
prefLabel
Defective T-cell receptor sign ...... eficient CD4+ CD8+ thymocytes.
@ast
Defective T-cell receptor sign ...... eficient CD4+ CD8+ thymocytes.
@en
P2093
P356
P1433
P1476
Defective T-cell receptor sign ...... eficient CD4+ CD8+ thymocytes.
@en
P2093
Barbacid M
Bernstein A
Fischer KD
Zmuldzinas A
P2888
P304
P356
10.1038/374474A0
P407
P577
1995-03-01T00:00:00Z
P6179
1045938146