Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia.
about
The adaptor protein Crk in immune responseBiosensors in clinical practice: focus on oncohematology.Domain organization differences explain Bcr-Abl's preference for CrkL over CrkIIUnc119 protects from Shigella infection by inhibiting the Abl family kinasesLoss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growthThe CRKL gene encoding an adaptor protein is amplified, overexpressed, and a possible therapeutic target in gastric cancer.Structural requirements for function of the Crkl adapter protein in fibroblasts and hematopoietic cells.Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors.Genetic interactions between the Drosophila Abelson (Abl) tyrosine kinase and failed axon connections (fax), a novel protein in axon bundles.Regulation of the interferon regulatory factor-8 (IRF-8) tumor suppressor gene by the signal transducer and activator of transcription 5 (STAT5) transcription factor in chronic myeloid leukemiaA therapeutically targetable mechanism of BCR-ABL-independent imatinib resistance in chronic myeloid leukemia.Expression and activity of Fyn mediate proliferation and blastic features of chronic myelogenous leukemia.Contribution of Crk adaptor proteins to host cell and bacteria interactions.PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia.Assaying Bcr-Abl kinase activity and inhibition in whole cell extracts by phosphorylation of substrates immobilized on agarose beads.Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis.Loss of the xeroderma pigmentosum group B protein binding site impairs p210 BCR/ABL1 leukemogenic activity.Acute dasatinib exposure commits Bcr-Abl-dependent cells to apoptosis.MicroRNA-320 inhibits invasion and induces apoptosis by targeting CRKL and inhibiting ERK and AKT signaling in gastric cancer cells.Abl Tyrosine Kinase Regulates Hepatitis C Virus EntryDasatinib targets chronic myeloid leukemia-CD34+ progenitors as effectively as it targets mature cells.The level of BCR-ABL1 kinase activity before treatment does not identify chronic myeloid leukemia patients who fail to achieve a complete cytogenetic response on imatinibA specific need for CRKL in p210BCR-ABL-induced transformation of mouse hematopoietic progenitors.Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia.
P2860
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P2860
Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia.
description
1994 nî lūn-bûn
@nan
1994 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia.
@ast
Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia.
@en
type
label
Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia.
@ast
Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia.
@en
prefLabel
Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia.
@ast
Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia.
@en
P2093
P1433
P1476
Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia.
@en
P2093
Arlinghaus RB
Heisterkamp N
ten Hoeve J
P304
P407
P577
1994-09-01T00:00:00Z