Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.
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Mechanisms of Hippo pathway regulationTargeting Mechanotransduction at the Transcriptional Level: YAP and BRD4 Are Novel Therapeutic Targets for the Reversal of Liver FibrosisThe mechanical regulation of integrin-cadherin crosstalk organizes cells, signaling and forcesMultiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix AdhesionDeregulation of the Hippo pathway in mouse mammary stem cells promotes mammary tumorigenesis.Regulation of localization and function of the transcriptional co-activator YAP by angiomotin.YAP regulates cell mechanics by controlling focal adhesion assembly.Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia.Fibronectin induces epithelial-mesenchymal transition in human breast cancer MCF-7 cells via activation of calpainYAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix MechanosensingαE-catenin inhibits a Src-YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway.A Computational Model of YAP/TAZ Mechanosensing.Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription.Disease implication of hyper-Hippo signalling.Glucocorticoid receptor signalling activates YAP in breast cancer.Jasplakinolide induces primary cilium formation through cell rounding and YAP inactivation.Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation.Platelet-derived growth factor regulates YAP transcriptional activity via Src family kinase dependent tyrosine phosphorylation.Transglutaminase Interaction with α6/β4-Integrin Stimulates YAP1-Dependent ΔNp63α Stabilization and Leads to Enhanced Cancer Stem Cell Survival and Tumor Formation.Integrin signalling regulates YAP and TAZ to control skin homeostasis.Endothelial cell-derived matrix promotes the metabolic functional maturation of hepatocyte via integrin-Src signalling.YAP and TAZ in epithelial stem cells: A sensor for cell polarity, mechanical forces and tissue damage.Cellular Organization and Cytoskeletal Regulation of the Hippo Signaling Network.Integrin-mediated mechanotransduction.Targeting the Hippo signalling pathway for cancer treatment.Functions and Epigenetic Regulation of Wwox in Bone Metastasis from Breast Carcinoma: Comparison with Primary Tumors.Focal adhesion kinase signaling in unexpected places.The role of Hippo/yes-associated protein signalling in vascular remodelling associated with cardiovascular disease.Cytokinesis Failure Leading to Chromosome Instability in v-Src-Induced Oncogenesis.Melatonin and Hippo Pathway: Is There Existing Cross-Talk?Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer.Combinatorial Microenvironments Impose a Continuum of Cellular Responses to a Single Pathway-Targeted Anti-cancer Compound.Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells.KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops.Mechanical control of growth: ideas, facts and challenges.Polo-Like Kinase 2 is Dynamically Regulated to Coordinate Proliferation and Early Lineage Specification Downstream of Yes-Associated Protein 1 in Cardiac Progenitor Cells.Influence of Mechanical Stimuli on Schwann Cell Biology.Sulforaphane reduces YAP/∆Np63α signaling to reduce cancer stem cell survival and tumor formation.Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis.Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression.
P2860
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P2860
Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.
description
2015 nî lūn-bûn
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2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.
@ast
Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.
@en
type
label
Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.
@ast
Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.
@en
prefLabel
Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.
@ast
Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.
@en
P2860
P356
P1476
Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.
@en
P2093
Barry M Gumbiner
Nam-Gyun Kim
P2860
P304
P356
10.1083/JCB.201501025
P407
P577
2015-07-27T00:00:00Z