Identical or overlapping sequences in the primary structure of human alpha(2)-macroglobulin are responsible for the binding of nerve growth factor-beta, platelet-derived growth factor-BB, and transforming growth factor-beta.

Identical or overlapping sequences in the primary structure of human alpha(2)-macroglobulin are responsible for the binding of nerve growth factor-beta, platelet-derived growth factor-BB, and transforming growth factor-beta.

Item
http://www.wikidata.org/entity/Q30304977
Further evidence for increased macrophage migration inhibitory factor expression in prostate cancer.Targeted Therapies in Liver Fibrosis: Combining the Best Parts of Platelet-Derived Growth Factor BB and Interferon GammaA 16-amino acid peptide from human alpha2-macroglobulin binds transforming growth factor-beta and platelet-derived growth factor-BB.Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors.Alpha2-macroglobulin is a mediator of retinal ganglion cell death in glaucoma.Prostate stem cells and benign prostatic hyperplasiaHepcidin bound to α2-macroglobulin reduces ferroportin-1 expression and enhances its activity at reducing serum iron levels.Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling.The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.Binding of alpha2-macroglobulin to GRAB (Protein G-related alpha2-macroglobulin-binding protein), an important virulence factor of group A streptococci, is mediated by two charged motifs in the DeltaA region.Characterization of the interaction between alpha2-macroglobulin and fibroblast growth factor-2: the role of hydrophobic interactions.Identification of the high affinity binding site in transforming growth factor-beta involved in complex formation with alpha 2-macroglobulin. Implications regarding the molecular mechanisms of complex formation between alpha 2-macroglobulin and growTGF-beta impairs renal autoregulation via generation of ROS.Limited mutations in full-length tetrameric human alpha2-macroglobulin abrogate binding of platelet-derived growth factor-BB and transforming growth factor-beta1.
P2860

Identical or overlapping sequences in the primary structure of human alpha(2)-macroglobulin are responsible for the binding of nerve growth factor-beta, platelet-derived growth factor-BB, and transforming growth factor-beta.

Item
http://www.wikidata.org/entity/Q30304977
description
2000 nî lūn-bûn
@nan
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Identical or overlapping seque ...... ansforming growth factor-beta.
@ast
Identical or overlapping seque ...... ansforming growth factor-beta.
@en
type
label
Identical or overlapping seque ...... ansforming growth factor-beta.
@ast
Identical or overlapping seque ...... ansforming growth factor-beta.
@en
prefLabel
Identical or overlapping seque ...... ansforming growth factor-beta.
@ast
Identical or overlapping seque ...... ansforming growth factor-beta.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P356
P1433
P1476
Identical or overlapping seque ...... ansforming growth factor-beta.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698