Smooth muscle myosin phosphatase-associated kinase induces Ca2+ sensitization via myosin phosphatase inhibition.
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Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscleRole of serine-threonine phosphoprotein phosphatases in smooth muscle contractilityPhosphorylation of the regulatory light chain of myosin in striated muscle: methodological perspectivesPar-4: a new activator of myosin phosphataseZIP kinase is responsible for the phosphorylation of myosin II and necessary for cell motility in mammalian fibroblastsFluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor.Overlapping roles of Drosophila Drak and Rok kinases in epithelial tissue morphogenesisA signal transduction pathway model prototype II: Application to Ca2+-calmodulin signaling and myosin light chain phosphorylationMAPKs represent novel therapeutic targets for gastrointestinal motility disorders.Enhanced contractility and myosin phosphorylation induced by Ca(2+)-independent MLCK activity in hypertensive ratsPhasic contractions of isolated human myometrium are associated with Rho-kinase (ROCK)-dependent phosphorylation of myosin phosphatase-targeting subunit (MYPT1).Regulation of myosin light chain phosphatase and pulmonary arterial relaxation.Delineating signal transduction pathways in smooth muscle through focused proteomics.The regulation of smooth muscle contractility by zipper-interacting protein kinase.Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.Endothelin and hepatic wound healing.Chemical genetics of zipper-interacting protein kinase reveal myosin light chain as a bona fide substrate in permeabilized arterial smooth muscle.Opportunities to Target Specific Contractile Abnormalities with Smooth Muscle Protein Kinase Inhibitors.Inhibition of zipper-interacting protein kinase function in smooth muscle by a myosin light chain kinase pseudosubstrate peptide.Integrin-linked kinase is responsible for Ca2+-independent myosin diphosphorylation and contraction of vascular smooth muscle.Mechanisms underlying potentiation of endothelin-1-induced myofilament Ca(2+) sensitization after subarachnoid hemorrhage.A novel inhibitory effect of oxazol-5-one compounds on ROCKII signaling in human coronary artery vascular smooth muscle cells.PHI-1 interacts with the catalytic subunit of myosin light chain phosphatase to produce a Ca(2+) independent increase in MLC(20) phosphorylation and force in avian smooth muscle.Gi-coupled receptors mediate phosphorylation of CPI-17 and MLC20 via preferential activation of the PI3K/ILK pathway.Cross-talk between Rho-associated kinase and cyclic nucleotide-dependent kinase signaling pathways in the regulation of smooth muscle myosin light chain phosphatase.Chronic hypoxia induces Rho kinase-dependent myogenic tone in small pulmonary arteries.Decreased phosphatase activity, increased Ca2+ sensitivity, and myosin light chain phosphorylation in urinary bladder smooth muscle of newborn mice.The pro-apoptotic protein Par-4 facilitates vascular contractility by cytoskeletal targeting of ZIPK.Increased myofibrillar protein phosphatase-1 activity impairs rat aortic smooth muscle activation after hypoxia.Dynamic changes in expression of myosin phosphatase in a model of portal hypertension.Actions downstream of cyclic GMP/protein kinase G can reverse protein kinase C-mediated phosphorylation of CPI-17 and Ca²⁺ sensitization in smooth muscle.Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to cyclic nucleotides.Ca2+-independent contraction of longitudinal ileal smooth muscle is potentiated by a zipper-interacting protein kinase pseudosubstrate peptide.Analysis of phosphorylation of the myosin-targeting subunit of myosin light chain phosphatase by Phos-tag SDS-PAGE.Increased basal phosphorylation of detrusor smooth muscle myosin in alloxan-induced diabetic rabbit is mediated by upregulation of Rho-kinase beta and CPI-17.Characterization of protein kinase pathways responsible for Ca2+ sensitization in rat ileal longitudinal smooth muscleStaurosporine inhibition of zipper-interacting protein kinase contractile effects in gastrointestinal smooth muscle
P2860
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P2860
Smooth muscle myosin phosphatase-associated kinase induces Ca2+ sensitization via myosin phosphatase inhibition.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Smooth muscle myosin phosphata ...... myosin phosphatase inhibition.
@ast
Smooth muscle myosin phosphata ...... myosin phosphatase inhibition.
@en
type
label
Smooth muscle myosin phosphata ...... myosin phosphatase inhibition.
@ast
Smooth muscle myosin phosphata ...... myosin phosphatase inhibition.
@en
prefLabel
Smooth muscle myosin phosphata ...... myosin phosphatase inhibition.
@ast
Smooth muscle myosin phosphata ...... myosin phosphatase inhibition.
@en
P2093
P2860
P356
P1476
Smooth muscle myosin phosphata ...... myosin phosphatase inhibition.
@en
P2093
Andrea Murányi
David J Hartshorne
Meredith A Borman
P2860
P304
23441-23446
P356
10.1074/JBC.M201597200
P407
P577
2002-04-25T00:00:00Z