In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
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Differential oxidation of two thiophene-containing regioisomers to reactive metabolites by cytochrome P450 2C9National Athletic Trainers' Association position statement: management of asthma in athletes.2-ABT-S-oxide detoxification by glutathione S-transferases A1-1, M1-1 and P1-1: implications for toxicity associated with zileuton.Regulation of leukotriene and 5oxoETE synthesis and the effect of 5-lipoxygenase inhibitors: a mathematical modeling approach.Identification of protein targets of reactive metabolites of tienilic acid in human hepatocytes.Role of metabolism in drug-induced idiosyncratic hepatotoxicity.Minimising the potential for metabolic activation in drug discovery.The potential link between atherosclerosis and the 5-lipoxygenase pathway: investigational agents with new implications for the cardiovascular field.Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order.Idiosyncratic reactions and metabolism of sulfur-containing drugs.Synthesis of benzothiophene and indole derivatives through metal-free propargyl-allene rearrangement and allyl migration.Computational Approach to Structural Alerts: Furans, Phenols, Nitroaromatics, and Thiophenes.New Caffeic Acid Phenylethyl Ester Analogs Bearing Substituted Triazole: Synthesis and Structure-Activity Relationship Study towards 5-Lipoxygenase Inhibition
P2860
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P2860
In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
@ast
In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
@en
type
label
In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
@ast
In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
@en
prefLabel
In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
@ast
In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
@en
P2093
P356
P1476
In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
@en
P2093
Brian H Heasley
Elizabeth M Joshi
Timothy L Macdonald
P304
P356
10.1021/TX0341409
P577
2004-02-01T00:00:00Z