Structural polymorphism of Alzheimer Abeta and other amyloid fibrils
about
Assessing the causes and consequences of co-polymerization in amyloid formationTransient dynamics of Aβ contribute to toxicity in Alzheimer's diseaseβ2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkagesA multiscale approach to characterize the early aggregation steps of the amyloid-forming peptide GNNQQNY from the yeast prion sup-35β-sheet propensity controls the kinetic pathways and morphologies of seeded peptide aggregation.Recent progress in understanding Alzheimer's β-amyloid structures.Atomic-resolution structure of a disease-relevant Aβ(1-42) amyloid fibril.Effects of membrane interaction and aggregation of amyloid β-peptide on lipid mobility and membrane domain structure.Polymorphism in Alzheimer Abeta amyloid organization reflects conformational selection in a rugged energy landscape.Human Tau isoforms assemble into ribbon-like fibrils that display polymorphic structure and stability.Prions: En route from structural models to structures.Kinetics of amyloid aggregation: a study of the GNNQQNY prion sequence.Amyloid features and neuronal toxicity of mature prion fibrils are highly sensitive to high pressureUnlocked concanavalin A forms amyloid-like fibrils from coagulation of long-lived "crinkled" intermediates.Conformational stability of fibrillar amyloid-beta oligomers via protofilament pair formation - a systematic computational studyMetAmyl: a METa-predictor for AMYLoid proteinsSynthesis and Self-Assembly of a Mikto-Arm Star Dual Drug Amphiphile Containing both Paclitaxel and Camptothecin.Systematic examination of polymorphism in amyloid fibrils by molecular-dynamics simulation.Nanomechanics and intermolecular forces of amyloid revealed by four-dimensional electron microscopy.Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongationStructural complexity of a composite amyloid fibril.Amyloid-like fibrils from a domain-swapping protein feature a parallel, in-register conformation without native-like interactions.Two distinct β-sheet structures in Italian-mutant amyloid-beta fibrils: a potential link to different clinical phenotypes.Mechanisms of kinetic trapping in self-assembly and phase transformation.Steric Crowding of the Turn Region Alters the Tertiary Fold of Amyloid-β18-35 and Makes It Soluble.Influence of the valine zipper region on the structure and aggregation of the basic leucine zipper (bZIP) domain of activating transcription factor 5 (ATF5).The emergence of superstructural order in insulin amyloid fibrils upon multiple rounds of self-seedingAFM-Based Single Molecule Techniques: Unraveling the Amyloid Pathogenic Species.Comparison of Alzheimer Abeta(1-40) and Abeta(1-42) amyloid fibrils reveals similar protofilament structures.Apoptosis induced by islet amyloid polypeptide soluble oligomers is neutralized by diabetes-associated specific antibodies.Context dependence of protein misfolding and structural strains in neurodegenerative diseases.Misfolded proteins and neurodegeneration: role of non-native cytochrome c in cell death.Amyloid structure--one but not the same: the many levels of fibrillar polymorphism.Neuropathology and biochemistry of Aβ and its aggregates in Alzheimer's disease.The route to protein aggregate superstructures: Particulates and amyloid-like spherulites.Lipopolysaccharide-binding protein (LBP) reverses the amyloid state of fibrin seen in plasma of type 2 diabetics with cardiovascular co-morbidities.Self-organizing bioinspired oligothiophene-oligopeptide hybrids.Application and use of differential scanning calorimetry in studies of thermal fluctuation associated with amyloid fibril formation.Charge dependent retardation of amyloid β aggregation by hydrophilic proteins.Chiral recognition in amyloid fiber growth.
P2860
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P2860
Structural polymorphism of Alzheimer Abeta and other amyloid fibrils
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural polymorphism of Alzheimer Abeta and other amyloid fibrils
@ast
Structural polymorphism of Alzheimer Abeta and other amyloid fibrils
@en
type
label
Structural polymorphism of Alzheimer Abeta and other amyloid fibrils
@ast
Structural polymorphism of Alzheimer Abeta and other amyloid fibrils
@en
prefLabel
Structural polymorphism of Alzheimer Abeta and other amyloid fibrils
@ast
Structural polymorphism of Alzheimer Abeta and other amyloid fibrils
@en
P2860
P356
P1433
P1476
Structural polymorphism of Alzheimer Abeta and other amyloid fibrils
@en
P2093
Jessica Meinhardt
Marcus Fändrich
P2860
P356
10.4161/PRI.3.2.8859
P577
2009-04-01T00:00:00Z