(R,S)-Reticuline 7-O-methyltransferase and (R,S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum - cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy.
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Three new O-methyltransferases are sufficient for all O-methylation reactions of ipecac alkaloid biosynthesis in root culture of Psychotria ipecacuanhaProduction of benzylisoquinoline alkaloids in Saccharomyces cerevisiaeEvaluation of Biosynthetic Pathway and Engineered Biosynthesis of AlkaloidsCrystal structure of norcoclaurine-6-O-methyltransferase, a key rate-limiting step in the synthesis of benzylisoquinoline alkaloidsCloning and characterization of a norbelladine 4'-O-methyltransferase involved in the biosynthesis of the Alzheimer's drug galanthamine in Narcissus sp. aff. pseudonarcissusProtein structure modeling indicates hexahistidine-tag interference with enzyme activity.The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum.A global approach to analysis and interpretation of metabolic data for plant natural product discovery.EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyzes the biosynthesis of xanthohumol.Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell culturesIntegration of deep transcript and targeted metabolite profiles for eight cultivars of opium poppy.Characterization of three O-methyltransferases involved in noscapine biosynthesis in opium poppy.RNAi-mediated replacement of morphine with the nonnarcotic alkaloid reticuline in opium poppy.Wound induced tanscriptional regulation of benzylisoquinoline pathway and characterization of wound inducible PsWRKY transcription factor from Papaver somniferum.Comparative transcriptome analysis using high papaverine mutant of Papaver somniferum reveals pathway and uncharacterized steps of papaverine biosynthesisThe Amaryllidaceae alkaloids: biosynthesis and methods for enzyme discovery.Benzylisoquinoline alkaloid metabolism: a century of discovery and a brave new world.Benzylisoquinoline alkaloid biosynthesis in opium poppy.Modern plant metabolomics: advanced natural product gene discoveries, improved technologies, and future prospects.Molecular modeling and site-directed mutagenesis reveal the benzylisoquinoline binding site of the short-chain dehydrogenase/reductase salutaridine reductase.Functional Characterization of 4'OMT and 7OMT Genes in BIA Biosynthesis.Identification of candidate genes involved in isoquinoline alkaloids biosynthesis in Dactylicapnos scandens by transcriptome analysis.Plant science. Morphinan biosynthesis in opium poppy requires a P450-oxidoreductase fusion protein.Proteins differentially expressed in elicited cell suspension culture of Podophyllum hexandrum with enhanced podophyllotoxin content.The new beta-D-glucosidase in terpenoid-isoquinoline alkaloid biosynthesis in Psychotria ipecacuanha.Opium poppy and Madagascar periwinkle: model non-model systems to investigate alkaloid biosynthesis in plants.The biosynthesis of papaverine proceeds via (S)-reticuline.Plant defense responses in opium poppy cell cultures revealed by liquid chromatography-tandem mass spectrometry proteomics.Systematic knockdown of morphine pathway enzymes in opium poppy using virus-induced gene silencing.Morphine biosynthesis in opium poppy involves two cell types: sieve elements and laticifers.Unraveling Additional O-Methylation Steps in Benzylisoquinoline Alkaloid Biosynthesis in California Poppy (Eschscholzia californica).Enhancement of alkaloid production in opium and California poppy by transactivation using heterologous regulatory factors.Structure, function, and evolution of plant O-methyltransferases.Integrated omics analysis of specialized metabolism in medicinal plants.Molecular cloning and characterization of tetrahydroprotoberberine cis-N-methyltransferase, an enzyme involved in alkaloid biosynthesis in opium poppy.Accelerating the semisynthesis of alkaloid-based drugs through metabolic engineering.Isolation and Characterization of O-methyltransferases Involved in the Biosynthesis of Glaucine in Glaucium flavum.Biochemical characterization of MelJ and MelK.Investigation of benzylisoquinoline alkaloid biosynthetic pathway and its transcriptional regulation in lotus.
P2860
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P2860
(R,S)-Reticuline 7-O-methyltransferase and (R,S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum - cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
(R,S)-Reticuline 7-O-methyltra ...... d biosynthesis in opium poppy.
@ast
(R,S)-Reticuline 7-O-methyltra ...... d biosynthesis in opium poppy.
@en
type
label
(R,S)-Reticuline 7-O-methyltra ...... d biosynthesis in opium poppy.
@ast
(R,S)-Reticuline 7-O-methyltra ...... d biosynthesis in opium poppy.
@en
prefLabel
(R,S)-Reticuline 7-O-methyltra ...... d biosynthesis in opium poppy.
@ast
(R,S)-Reticuline 7-O-methyltra ...... d biosynthesis in opium poppy.
@en
P2093
P1433
P1476
(R,S)-Reticuline 7-O-methyltra ...... d biosynthesis in opium poppy.
@en
P2093
Anan Ounaroon
Friedrich Lottspeich
Gabriele Decker
Jürgen Schmidt
Toni M Kutchan
P304
P356
10.1046/J.1365-313X.2003.01928.X
P577
2003-12-01T00:00:00Z