The 1918 Spanish influenza: integrating history and biology.
about
Integrating historical, clinical and molecular genetic data in order to explain the origin and virulence of the 1918 Spanish influenza virusExisting antivirals are effective against influenza viruses with genes from the 1918 pandemic virus.Pandemic influenza threat and preparednessBygiene: The New Paradigm of Bidirectional HygieneConserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B virusesStructural basis for dsRNA recognition by NS1 protein of influenza A virusStructural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA EndonucleaseConformational polymorphism of m7GTP in crystal structure of the PB2 middle domain from human influenza A virusCrystallization and preliminary X-ray diffraction studies of a surface mutant of the middle domain of PB2 from human influenza A (H1N1) virusInfluenza: old and new threatsThe 1918-1920 influenza pandemic in Peru.1918 influenza pandemic caused by highly conserved viruses with two receptor-binding variants.Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus.Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus.Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in miceThe CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target.Progress in identifying virulence determinants of the 1918 H1N1 and the Southeast Asian H5N1 influenza A viruses.Emerging antiviral targets for influenza A virus.The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact pathogenesisStructures of influenza A proteins and insights into antiviral drug targets.Pandemic H1N1 influenza virus causes a stronger inflammatory response than seasonal H1N1 influenza virus in ferrets.Design, synthesis, and evaluation of novel small molecule inhibitors of the influenza virus protein NS1.Novel inhibitor of influenza non-structural protein 1 blocks multi-cycle replication in an RNase L-dependent manner.Understanding the evolutionary relationship of hemagglutinin protein from influenza viruses using phylogenetic and molecular modeling studies.Novel influenza virus NS1 antagonists block replication and restore innate immune function.Molecular restoration of archived transcriptional profiles by complementary-template reverse-transcription (CT-RT).1918 influenza: a Winnebago County, Wisconsin perspective.Bordetella pertussis infection exacerbates influenza virus infection through pertussis toxin-mediated suppression of innate immunityThe natural host range shift and subsequent evolution of canine parvovirus resulted from virus-specific binding to the canine transferrin receptorViral parkinsonism.The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway.The human/animal interface: emergence and resurgence of zoonotic infectious diseases.The TLR4 antagonist Eritoran protects mice from lethal influenza infection.Influenza: the virus and prophylaxis with inactivated influenza vaccine in "at risk" groups, including COPD patientsProtein intrinsic disorder and influenza virulence: the 1918 H1N1 and H5N1 viruses.Kinetics of pulmonary immune cells, antibody responses and their correlations with the viral clearance of influenza A fatal infection in mice.Interspecies and intraspecies transmission of influenza A viruses: viral, host and environmental factors.Secondary Bacterial Infections Associated with Influenza PandemicsSituating mortality: quantifying crisis points and periods of stability.Molecular dynamics simulation of the effects of single (S221P) and double (S221P and K216E) mutations in the hemagglutinin protein of influenza A H5N1 virus: a study on host receptor specificity.
P2860
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P2860
The 1918 Spanish influenza: integrating history and biology.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The 1918 Spanish influenza: integrating history and biology.
@ast
The 1918 Spanish influenza: integrating history and biology.
@en
type
label
The 1918 Spanish influenza: integrating history and biology.
@ast
The 1918 Spanish influenza: integrating history and biology.
@en
prefLabel
The 1918 Spanish influenza: integrating history and biology.
@ast
The 1918 Spanish influenza: integrating history and biology.
@en
P50
P1476
The 1918 Spanish influenza: integrating history and biology.
@en
P356
10.1016/S1286-4579(00)01351-4
P577
2001-01-01T00:00:00Z