Natural variation can significantly alter the sensitivity of influenza A (H5N1) viruses to oseltamivir.
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Effect of neuraminidase inhibitor-resistant mutations on pathogenicity of clade 2.2 A/Turkey/15/06 (H5N1) influenza virus in ferretsNovel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibilityEnhanced mammalian transmissibility of seasonal influenza A/H1N1 viruses encoding an oseltamivir-resistant neuraminidaseOseltamivir is adequately absorbed following nasogastric administration to adult patients with severe H5N1 influenzaI222 Neuraminidase mutations further reduce oseltamivir susceptibility of Indonesian Clade 2.1 highly pathogenic Avian Influenza A(H5N1) virusesUse of highly pathogenic avian influenza A(H5N1) gain-of-function studies for molecular-based surveillance and pandemic preparedness.Neuraminidase inhibitor-resistant recombinant A/Vietnam/1203/04 (H5N1) influenza viruses retain their replication efficiency and pathogenicity in vitro and in vivo.Cost-effectiveness of antiviral stockpiling and near-patient testing for potential influenza pandemic.Detection of molecular markers of antiviral resistance in influenza A (H5N1) viruses using a pyrosequencing method.Susceptibility of highly pathogenic H5N1 influenza viruses to the neuraminidase inhibitor oseltamivir differs in vitro and in a mouse model.Emergence of H5N1 avian influenza viruses with reduced sensitivity to neuraminidase inhibitors and novel reassortants in Lao People's Democratic Republic.Oseltamivir in human avian influenza infection.Molecular dynamics simulation of oseltamivir resistance in neuraminidase of avian influenza H5N1 virus.Treatment options for H5N1: lessons learned from the H1N1 pandemic.Neuraminidase inhibitor sensitivity and receptor-binding specificity of Cambodian clade 1 highly pathogenic H5N1 influenza virusA(H5N1) Virus Evolution in South East Asia.Update on influenza diagnostics: lessons from the novel H1N1 influenza A pandemicI223R mutation in influenza A(H1N1)pdm09 neuraminidase confers reduced susceptibility to oseltamivir and zanamivir and enhanced resistance with H275YSpatiotemporal circulation of influenza viruses in 5 African countries during 2008-2009: a collaborative study of the Institut Pasteur International Network.Consequences of resistance: in vitro fitness, in vivo infectivity, and transmissibility of oseltamivir-resistant influenza A viruses.Antiviral resistance among highly pathogenic influenza A (H5N1) viruses isolated worldwide in 2002-2012 shows need for continued monitoring.Characterization of the influenza A H5N1 viruses of the 2008-09 outbreaks in India reveals a third introduction and possible endemicity.Enzymatic properties of the neuraminidase of seasonal H1N1 influenza viruses provide insights for the emergence of natural resistance to oseltamivir.Enhancement of the influenza A hemagglutinin (HA)-mediated cell-cell fusion and virus entry by the viral neuraminidase (NA).A genetically engineered waterfowl influenza virus with a deletion in the stalk of the neuraminidase has increased virulence for chickens.Reduced sensitivity of influenza A (H5N1) to oseltamivirA molecular and antigenic survey of H5N1 highly pathogenic avian influenza virus isolates from smallholder duck farms in Central Java, Indonesia during 2007-2008.Functional balance between the hemagglutinin and neuraminidase of influenza A(H1N1)pdm09 HA D222 variants.Genetic characterization of H5N1 influenza viruses isolated from chickens in Indonesia in 2010.Detection sensitivity of influenza rapid diagnostic testsDetermination of neuraminidase kinetic constants using whole influenza virus preparations and correction for spectroscopic interference by a fluorogenic substrateCombinatorial effect of two framework mutations (E119V and I222L) in the neuraminidase active site of H3N2 influenza virus on resistance to oseltamivirEffect of an asparagine-to-serine mutation at position 294 in neuraminidase on the pathogenicity of highly pathogenic H5N1 influenza A virusMolecular mechanisms underlying oseltamivir resistance mediated by an I117V substitution in the neuraminidase of subtype H5N1 avian influenza A viruses.Neuraminidase stalk length and additional glycosylation of the hemagglutinin influence the virulence of influenza H5N1 viruses for miceThe significance of naturally occurring neuraminidase quasispecies of H5N1 avian influenza virus on resistance to oseltamivir: a point of concernInfluenza A virus neuraminidase enhances meningococcal adhesion to epithelial cells through interaction with sialic acid-containing meningococcal capsules.Influenza genome analysis using pyrosequencing method: current applications for a moving target.Influenza neuraminidase: a druggable target for natural products.
P2860
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P2860
Natural variation can significantly alter the sensitivity of influenza A (H5N1) viruses to oseltamivir.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Natural variation can signific ...... (H5N1) viruses to oseltamivir.
@ast
Natural variation can signific ...... (H5N1) viruses to oseltamivir.
@en
type
label
Natural variation can signific ...... (H5N1) viruses to oseltamivir.
@ast
Natural variation can signific ...... (H5N1) viruses to oseltamivir.
@en
prefLabel
Natural variation can signific ...... (H5N1) viruses to oseltamivir.
@ast
Natural variation can signific ...... (H5N1) viruses to oseltamivir.
@en
P2093
P2860
P356
P1476
Natural variation can signific ...... (H5N1) viruses to oseltamivir.
@en
P2093
Rameix-Welti MA
van der Werf S
P2860
P304
P356
10.1128/AAC.00645-06
P407
P577
2006-08-28T00:00:00Z