Mechanical unfolding of proteins: insights into biology, structure and folding.
about
Conformational equilibria in monomeric alpha-synuclein at the single-molecule levelIntramolecular isopeptide bonds give thermodynamic and proteolytic stability to the major pilin protein of Streptococcus pyogenesHierarchies, multiple energy barriers, and robustness govern the fracture mechanics of alpha-helical and beta-sheet protein domainsStructural basis for unfolding pathway-dependent stability of proteins: Vectorial unfolding versus global unfoldingLatent TGF-β structure and activationIsopeptide bonds block the mechanical extension of pili in pathogenic Streptococcus pyogenesThe regulation of N-methyl-D-aspartate receptors by Src kinase.Molecular basis for the structural stability of an enclosed β-barrel loop.Unfolding times for proteins in a force clamp.Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing.On the remarkable mechanostability of scaffoldins and the mechanical clamp motif.Mechanical unfolding of an ankyrin repeat protein.Protein high-force pulling simulations yield low-force results.Protein folding studied by single-molecule FRET.Towards design principles for determining the mechanical stability of proteins.Protein unfolding under force: crack propagation in a network.Revealing the bifurcation in the unfolding pathways of GFP by using single-molecule experiments and simulations.Fibers with integrated mechanochemical switches: minimalistic design principles derived from fibronectinVisualizing myosin-actin interaction with a genetically-encoded fluorescent strain sensor.The effects of macromolecular crowding on the mechanical stability of protein molecules.Mechanical stability and differentially conserved physical-chemical properties of titin Ig-domains.Tightening the knot in phytochrome by single-molecule atomic force microscopy.Understanding biology by stretching proteins: recent progress.Ultrafast hydrogen exchange reveals specific structural events during the initial stages of folding of cytochrome cMethods of probing the interactions between small molecules and disordered proteins.An effective strategy for the design of proteins with enhanced mechanical stability.Non-native interactions are critical for mechanical strength in PKD domains.Protein-DNA chimeras for single molecule mechanical folding studies with the optical tweezers.The effect of temperature on mechanical resistance of the native and intermediate states of I27.The molecular mechanism underlying mechanical anisotropy of the protein GB1.Engineering proteins with enhanced mechanical stability by force-specific sequence motifs.Tracking unfolding and refolding reactions of single proteins using atomic force microscopy methodsMechanical unfolding of acylphosphatase studied by single-molecule force spectroscopy and MD simulations.Single molecule force spectroscopy reveals that electrostatic interactions affect the mechanical stability of proteins.Mechanical unfolding of covalently linked GroES: evidence of structural subunit intermediates.Evidence of a folding intermediate in RNase H from single-molecule FRET experiments.Unfolding of a comb-like polymer in a poor solvent: translation of macromolecular architecture in the force-deformation spectra.Effects of ligand binding on the mechanical stability of protein GB1 studied by steered molecular dynamics simulation.Engineering strain-sensitive yellow fluorescent protein.Modeling Protein Folding Pathways
P2860
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P2860
Mechanical unfolding of proteins: insights into biology, structure and folding.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Mechanical unfolding of proteins: insights into biology, structure and folding.
@ast
Mechanical unfolding of proteins: insights into biology, structure and folding.
@en
type
label
Mechanical unfolding of proteins: insights into biology, structure and folding.
@ast
Mechanical unfolding of proteins: insights into biology, structure and folding.
@en
prefLabel
Mechanical unfolding of proteins: insights into biology, structure and folding.
@ast
Mechanical unfolding of proteins: insights into biology, structure and folding.
@en
P1476
Mechanical unfolding of proteins: insights into biology, structure and folding.
@en
P2093
Jane Clarke
Julia R Forman
P356
10.1016/J.SBI.2007.01.006
P577
2007-01-23T00:00:00Z