Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET
about
Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious useMultiply labeling proteins for studies of folding and stabilityEfficient genetic encoding of phosphoserine and its nonhydrolyzable analogForced Ambiguity of the Leucine Codons for Multiple-Site-Specific Incorporation of a Noncanonical Amino AcidRepurposing the translation apparatus for synthetic biologyBioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids.Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET.Polyspecific pyrrolysyl-tRNA synthetases from directed evolutionReducing the genetic code induces massive rearrangement of the proteome.Histones: at the crossroads of peptide and protein chemistry.Semisynthetic protein nanoreactor for single-molecule chemistrySite-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne.Rationally evolving tRNAPyl for efficient incorporation of noncanonical amino acidsComparison of strategies for non-perturbing labeling of α-synuclein to study amyloidogenesis.Dual Genetic Encoding of Acetyl-lysine and Non-deacetylatable Thioacetyl-lysine Mediated by FlexizymeEfficient Reassignment of a Frequent Serine Codon in Wild-Type Escherichia coli.[Dual genetic encoding of acetyl-lysine and non-deacetylatablethioacetyl-lysine mediated by flexizyme].Illuminating biological processes through site-specific protein labeling.Copper-Free Postsynthetic Labeling of Nucleic Acids by Means of Bioorthogonal Reactions.Overcoming Challenges in Engineering the Genetic CodeIncorporation of Non-Canonical Amino Acids.Systematic Evolution and Study of UAGN Decoding tRNAs in a Genomically Recoded Bacteria.Towards the next generation of biomedicines by site-selective conjugation.Biocatalysis with Unnatural Amino Acids: Enzymology Meets Xenobiology.Bioorthogonal Click Chemistry-Based Synthetic Cell GlueInverse Electron-Demand Diels-Alder Bioorthogonal Reactions.Self-assembling peptide-based building blocks in medical applications.Rapid in vitro screening for the location-dependent effects of unnatural amino acids on protein expression and activity.Site-selective protein-modification chemistry for basic biology and drug development.Rewiring host activities for synthetic circuit production: a translation view.Designing logical codon reassignment - Expanding the chemistry in biology.Bio-orthogonal Fluorescent Labelling of Biopolymers through Inverse-Electron-Demand Diels-Alder ReactionsThe central role of tRNA in genetic code expansion.A FRET-based method for monitoring septin polymerization and binding of septin-associated proteinsReal-time label-free quantitative fluorescence microscopy-based detection of ATP using a tunable fluorescent nano-aptasensor platform.Fluorescence imaging of chromosomal DNA using click chemistry.Defining synonymous codon compression schemes by genome recoding.Synthetic genome recoding: new genetic codes for new features.Molecular-scale GPS: positioning a biosensor peptide on RyR.Ribosome Subunit Stapling for Orthogonal Translation in E. coli.
P2860
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P2860
Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Optimized orthogonal translati ...... tein double-labelling and FRET
@ast
Optimized orthogonal translati ...... tein double-labelling and FRET
@en
type
label
Optimized orthogonal translati ...... tein double-labelling and FRET
@ast
Optimized orthogonal translati ...... tein double-labelling and FRET
@en
prefLabel
Optimized orthogonal translati ...... tein double-labelling and FRET
@ast
Optimized orthogonal translati ...... tein double-labelling and FRET
@en
P2093
P2860
P356
P1433
P1476
Optimized orthogonal translati ...... tein double-labelling and FRET
@en
P2093
Amit Sachdeva
Daniel J Cox
Jason W Chin
Kathrin Lang
Nabil M Wilf
Ryan A Mehl
P2860
P2888
P304
P356
10.1038/NCHEM.1919
P577
2014-04-20T00:00:00Z
P5875
P6179
1017989024