On the role of uncoupling protein-2 in pancreatic beta cells.
about
Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen speciesDynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cellsMitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities.Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespanInteraction between the UCP2 -866 G>A polymorphism, diabetes, and beta-blocker use among patients with acute coronary syndromes.Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male miceUncoupling protein-2 mediates the protective action of berberine against oxidative stress in rat insulinoma INS-1E cells and in diabetic mouse islets.The regulation and turnover of mitochondrial uncoupling proteins.Glucose sensing in the pancreatic beta cell: a computational systems analysis.Mitochondrial uncoupling and lifespan.Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice.Resveratrol ameliorates the maturation process of β-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cellsMechanisms of glucose sensing in the pancreatic β-cell: A computational systems-based analysis.Glutathionylation state of uncoupling protein-2 and the control of glucose-stimulated insulin secretion.Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.A 45-bp insertion/deletion polymorphism of UCP2 gene is associated with metabolic syndrome.The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complications.Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress.Mitochondrial dynamics and morphology in beta-cells.Mitochondrial oxidative metabolism and uncoupling proteins in the failing heart.Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells.The Pancreatic β-Cell: A Bioenergetic Perspective.Uncoupling protein 2 and metabolic diseases.Acetoacetate reduces growth and ATP concentration in cancer cell lines which over-express uncoupling protein 2.Analysis and update of the human solute carrier (SLC) gene superfamilyMitochondria and the regulation of free radical damage in the eye.Mitochondrial uncoupling protein-2 is not involved in palmitate-induced impairment of glucose-stimulated insulin secretion in INS-1E insulinoma cells and is not needed for the amplification of insulin release.Intolerant of glucose and gasping for oxygen.
P2860
Q28565465-F8F82596-153C-425C-93CB-8E7B442DD7F6Q28574719-71ABC421-02E1-4345-9229-1447223D1001Q33668501-3A65599D-219C-4D8C-B2FD-245D646B83F3Q33694302-8DE0AE89-8999-4C29-846A-0193875322F5Q33742128-6CF51589-FAA5-4F7A-85D3-490EB9340C6DQ33836038-BF328C99-C4BD-44CF-9B03-8C6BE705D595Q33842742-33EFA772-5FDF-43A1-81EF-0419D595A9E4Q33936374-A1CACB58-6962-4169-868C-BF8D50E75A81Q33961250-B17CA279-CD74-443E-A705-6F7D9710E1AEQ34077042-3B83C89E-7FC3-4B57-ABEA-0181B0FD4641Q34115152-7CC3F8B7-7C4A-45A8-AA4A-9D6FE42B895FQ34537129-E40CCE2D-9089-452C-86E2-4E53B1323248Q35182244-88E73BF9-D76F-404F-8468-B3E93624E466Q35558863-7CEEB358-562A-4D3A-928E-5E1AF059422CQ36407981-765123A8-B4FE-471A-8A41-F057F0F56FE1Q37341488-D6C120AD-1333-432E-ADC9-4095791BA2E4Q37607704-42E0F803-5394-4184-94FA-F00F70613E7BQ37903726-603DDC5D-E90F-4242-95F9-773CF327A5DCQ37976675-F217284E-AF0D-44D6-A07C-5875A5DCE8CFQ38061271-5A7C8331-706F-45AC-B4BB-53C0BFBC1477Q38246367-E2275CF3-B160-4CCB-9207-53DE55D25DEFQ38931580-B55E32A2-BA07-4289-8E04-DAC4CC3AC216Q38943061-3DA81CD9-8EEF-47A2-BA46-ECC7D596DA14Q39205505-64504BE1-CE3E-4663-99A1-BB64A4693DA5Q41550485-5A99E0F4-DF02-474B-A7FD-730D5E89A570Q41857194-1D376369-225D-4566-A3CC-17CDCF9715C9Q42127171-D095F79D-059B-439A-BA97-79D9B3F05755Q42763181-4681D302-1322-4428-A19A-3FA462A6CBC4Q46098213-25DAC4A1-DEA7-431C-99E2-BC711C770A94
P2860
On the role of uncoupling protein-2 in pancreatic beta cells.
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
On the role of uncoupling protein-2 in pancreatic beta cells.
@ast
On the role of uncoupling protein-2 in pancreatic beta cells.
@en
type
label
On the role of uncoupling protein-2 in pancreatic beta cells.
@ast
On the role of uncoupling protein-2 in pancreatic beta cells.
@en
prefLabel
On the role of uncoupling protein-2 in pancreatic beta cells.
@ast
On the role of uncoupling protein-2 in pancreatic beta cells.
@en
P1476
On the role of uncoupling protein-2 in pancreatic beta cells.
@en
P2093
Charles Affourtit
Martin D Brand
P304
P356
10.1016/J.BBABIO.2008.03.022
P407
P577
2008-04-03T00:00:00Z