The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.
about
X-ray structure and inhibition of the feline infectious peritonitis virus 3C-like protease: Structural implications for drug designCoronaviruses and the human airway: a universal system for virus-host interaction studiesPotent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.Detection and characterization of diverse alpha- and betacoronaviruses from bats in China.SARS hCoV papain-like protease is a unique Lys48 linkage-specific di-distributive deubiquitinating enzymeExtensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C Betacoronaviruses.p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design.Recent progress in the discovery of inhibitors targeting coronavirus proteases.Monitoring Target Engagement of Deubiquitylating Enzymes Using Activity Probes: Past, Present, and Future.SARS-CoV-Encoded Small RNAs Contribute to Infection-Associated Lung Pathology.Computational and Experimental Studies of ADP-Ribosylation.Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication.Adaptive evolution influences the infectious dose of MERS-CoV necessary to achieve severe respiratory disease.Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.Inhibition of USP10 induces degradation of oncogenic FLT3.Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element.Host resilience to emerging coronaviruses
P2860
Q27702869-7C6FA8C8-87C5-4F14-973E-7E4C8942C355Q28075580-2E76C764-C1CB-43E2-8745-2EC31702C752Q30145557-ECBFFE8C-4F7D-4FD6-9865-0E7E6F39D416Q31043167-AE17257C-ACAC-4EA5-9B49-16DA1DC181B6Q35660049-BCB58E84-6698-4BB4-9FEE-6F5105DCDA6DQ36694030-287888E5-7F46-410C-8702-108C17EBD94CQ37258617-E687FED0-1740-4D88-8796-EC4804DCD0B4Q37581697-07AB5D13-C64F-463C-A27C-7E59659F54BDQ38752322-ACAEE6A2-D332-4D83-8693-C17020D9D03CQ38822748-174B4C16-99C9-4AF5-912E-982B0F02EA66Q38952916-B3CDF281-B51E-4B1D-B519-E7D4F5632F16Q40127884-DA1CC7D0-C2A8-4FAE-A8BC-C0AA7810FD36Q46033198-DCAD1462-18AD-48A0-8A78-71ED3A3DE17EQ47250328-691C5CC2-2B93-4FAC-B07C-991CCD5537A8Q47619828-26763591-5A6B-4A15-9A2B-688423DB5EAAQ47716589-4495FB75-56D2-4DE3-A79F-8418CA505CDDQ52653879-CE5A4C13-4E1E-417F-B60E-1166181C0C7FQ57206349-0C8E6003-D91D-49CB-BBF0-0BA0CDB671E8
P2860
The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The SARS-coronavirus papain-li ...... designed antiviral compounds.
@ast
The SARS-coronavirus papain-li ...... designed antiviral compounds.
@en
type
label
The SARS-coronavirus papain-li ...... designed antiviral compounds.
@ast
The SARS-coronavirus papain-li ...... designed antiviral compounds.
@en
prefLabel
The SARS-coronavirus papain-li ...... designed antiviral compounds.
@ast
The SARS-coronavirus papain-li ...... designed antiviral compounds.
@en
P2093
P2860
P1433
P1476
The SARS-coronavirus papain-li ...... designed antiviral compounds.
@en
P2093
Andrew D Mesecar
Sarah E St John
Yahira M Báez-Santos
P2860
P356
10.1016/J.ANTIVIRAL.2014.12.015
P577
2014-12-29T00:00:00Z