Direct observation of the dynamic process underlying allosteric signal transmission.
about
Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer?Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutationsNMR Methods to Study Dynamic AllosteryDirect and Propagated Effects of Small Molecules on Protein-Protein Interaction NetworksEngineering an allosteric binding site for aminoglycosides into TEM1-β-LactamaseOrdering a Dynamic Protein Via a Small-Molecule StabilizerAllosteric Communication in the KIX Domain Proceeds through Dynamic Repacking of the Hydrophobic CoreCooperative structure of the heterotrimeric pre-mRNA retention and splicing complexStudying Dynamics by Magic-Angle Spinning Solid-State NMR Spectroscopy: Principles and Applications to BiomoleculesInteraction energy based protein structure networksModeling allosteric signal propagation using protein structure networksRole of long- and short-range hydrophobic, hydrophilic and charged residues contact network in protein's structural organization.Insight into the role of dynamics in the conformational switch of the small GTP-binding protein Arf1Longitudinal relaxation enhancement in 1H NMR spectroscopy of tissue metabolites via spectrally selective excitation.Relaxation dispersion NMR spectroscopy for the study of protein allosteryChemical exchange in biomacromolecules: past, present, and future.Prepaying the entropic cost for allosteric regulation in KIXAllostery within a transcription coactivator is predominantly mediated through dissociation rate constantsDissecting allosteric effects of activator-coactivator complexes using a covalent small molecule ligand.Conformational control of the binding of the transactivation domain of the MLL protein and c-Myb to the KIX domain of CREBMolecular recognition by the KIX domain and its role in gene regulation.An introduction to NMR-based approaches for measuring protein dynamics.Site-resolved measurement of microsecond-to-millisecond conformational-exchange processes in proteins by solid-state NMR spectroscopyMolecular Recognition by Templated Folding of an Intrinsically Disordered ProteinColocalization of fast and slow timescale dynamics in the allosteric signaling protein CheYSekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.Multiple pathways promote dynamical coupling between catalytic domains in Escherichia coli prolyl-tRNA synthetase.The allosteric communication pathways in KIX domain of CBPThe origin of allosteric functional modulation: multiple pre-existing pathways.NMR spectroscopy brings invisible protein states into focus.NMR reveals novel mechanisms of protein activity regulation.Specific 12CβD(2)12CγD(2)S13CεHD(2) isotopomer labeling of methionine to characterize protein dynamics by 1H and 13C NMR relaxation dispersion.Nanometer propagation of millisecond motions in V-type allostery.The archaeal exosome: identification and quantification of site-specific motions that correlate with cap and RNA binding.Segmental motions, not a two-state concerted switch, underlie allostery in CheY.The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb.Discerning intersecting fusion-activation pathways in the Nipah virus using machine learning.Millisecond dynamics in the allosteric enzyme imidazole glycerol phosphate synthase (IGPS) from Thermotoga maritima.Profiling the dynamic interfaces of fluorinated transcription complexes for ligand discovery and characterization.Conformational exchange of aromatic side chains characterized by L-optimized TROSY-selected ¹³C CPMG relaxation dispersion.
P2860
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P2860
Direct observation of the dynamic process underlying allosteric signal transmission.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Direct observation of the dynamic process underlying allosteric signal transmission.
@ast
Direct observation of the dynamic process underlying allosteric signal transmission.
@en
type
label
Direct observation of the dynamic process underlying allosteric signal transmission.
@ast
Direct observation of the dynamic process underlying allosteric signal transmission.
@en
prefLabel
Direct observation of the dynamic process underlying allosteric signal transmission.
@ast
Direct observation of the dynamic process underlying allosteric signal transmission.
@en
P2093
P356
P1476
Direct observation of the dynamic process underlying allosteric signal transmission.
@en
P2093
Georg Kontaxis
Karin Kloiber
Martin Tollinger
Robert Konrat
Sven Brüschweiler
P304
P356
10.1021/JA809947W
P407
P577
2009-03-01T00:00:00Z