Human glia can both induce and rescue aspects of disease phenotype in Huntington disease. - Wikidata - awgldk - TriplyDB

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

http://www.wikidata.org/entity/Q30381085

about

Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease.Protective Microglia and Their Regulation in Parkinson's Disease Microglial Activation in the Pathogenesis of Huntington's Disease.Humanized neuronal chimeric mouse brain generated by neonatally engrafted human iPSC-derived primitive neural progenitor cells.Protein misfolding in neurodegenerative diseases: implications and strategies.Sensory response in host and engrafted astrocytes of adult brain in Vivo.Unravelling and Exploiting Astrocyte Dysfunction in Huntington's Disease.Human astrocytes are distinct contributors to the complexity of synaptic function.Progenitor cell-based treatment of glial disease.SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions.Neurodegenerative disease: Glial cells - friend and foe in Huntington disease?HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo.Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice.Migratory potential of transplanted glial progenitors as critical factor for successful translation of glia replacement therapy: The gap between mice and men.Clinical implications of myelin regeneration in the central nervous system.Synergistic Toxicity of Polyglutamine-Expanded TATA-Binding Protein in Glia and Neuronal Cells: Therapeutic Implications for Spinocerebellar Ataxia 17.Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function.Pathway-Specific Control of Striatal Neuron Vulnerability by Corticostriatal Cannabinoid CB1 Receptors.Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy.hPSC-Derived Striatal Cells Generated Using a Scalable 3D Hydrogel Promote Recovery in a Huntington Disease Mouse Model.Supplemental Treatment for Huntington's Disease with miR-132 that Is Deficient in Huntington's Disease Brain.Metformin treatment ameliorates diabetes‐associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1.Removal of the Mitochondrial Fission Factor Mff Exacerbates Neuronal Loss and Neurological Phenotypes in a Huntington's Disease Mouse Model The Role of Adenosine Tone and Adenosine Receptors in Huntington's Disease

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P2860

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

http://www.wikidata.org/entity/Q30381085

description

2016 nî lūn-bûn

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2016 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի հունիսին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

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name

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

@ast

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

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type

label

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

@ast

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

@en

prefLabel

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

@ast

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

@en

P1433

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P1433

Nature Communications

P1476

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

@en

P2093

Abdellatif Benraiss

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Daniela Brunner

http://www.w3.org/2001/XMLSchema#string

Devin Chandler-Militello

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Fengfei Ding

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Fushun Wang

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Hayley B Burm

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Ignacio Munoz-Sanjuan

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Jian Kang

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Joseph Mauceri

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Martha S Windrem

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P2860

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

High-throughput analysis of behavior for drug discovery

Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation

High-Throughput Automated Phenotyping of Two Genetic Mouse Models of Huntington's Disease

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease

Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse

Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.

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11758

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scholarly article

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10.1038/NCOMMS11758

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P478

7

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Maiken Nedergaard

Steven A. Goldman

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2016-06-07T00:00:00Z

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1006612361

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27273432

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Huntington disease

P932

4899632

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