An αIIb mutation in patients with Glanzmann thrombasthenia located in the N-terminus of blade 1 of the β-propeller (Asn2Asp) disrupts a calcium binding site in blade 6.
about
Congenital platelet disorders and understanding of platelet function.Glanzmann thrombasthenia: state of the art and future directions.A single disulfide bond disruption in the β3 integrin subunit promotes thiol/disulfide exchange, a molecular dynamics study.Molecular dynamics analysis of a novel β3 Pro189Ser mutation in a patient with glanzmann thrombasthenia differentially affecting αIIbβ3 and αvβ3 expression.Understanding the genetic basis of Glanzmann thrombasthenia: implications for treatment.Natural and artificial mutations in αIIb integrin lead to a structural deformation of a calcium-binding site.In silico analysis of Glanzmann variants of Calf-1 domain of αIIbβ3 integrin revealed dynamic allosteric effect.Expanding the Mutation Spectrum Affecting αIIbβ3 Integrin in Glanzmann Thrombasthenia: Screening of the ITGA2B and ITGB3 Genes in a Large International Cohort.
P2860
Q33411778-E7DD8288-2EF5-4430-B358-5B8771AD48DEQ33571529-6AF30A2E-F62D-404D-B5E1-E46E21B4F505Q34634757-C2F5D73D-451B-481F-A6EE-4E82656B9671Q35043549-67834A71-327A-4AD6-A76C-B1FF7BB3625BQ38059249-DB518052-AAB7-4832-9759-EF781E7CE2A0Q38957041-02B286A5-2EF7-413A-8A5A-3BDFDEB4D57DQ41387577-F4CC9BF0-87FE-41E8-958D-F16CC6CEE662Q49155547-A7CFCBE5-7C4E-430E-807C-F721DBB16B8F
P2860
An αIIb mutation in patients with Glanzmann thrombasthenia located in the N-terminus of blade 1 of the β-propeller (Asn2Asp) disrupts a calcium binding site in blade 6.
description
2011 nî lūn-bûn
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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2011 թվականի հունվարին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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name
An αIIb mutation in patients w ...... lcium binding site in blade 6.
@ast
An αIIb mutation in patients w ...... lcium binding site in blade 6.
@en
type
label
An αIIb mutation in patients w ...... lcium binding site in blade 6.
@ast
An αIIb mutation in patients w ...... lcium binding site in blade 6.
@en
prefLabel
An αIIb mutation in patients w ...... lcium binding site in blade 6.
@ast
An αIIb mutation in patients w ...... lcium binding site in blade 6.
@en
P2093
P2860
P1476
An αIIb mutation in patients w ...... lcium binding site in blade 6.
@en
P2093
P2860
P304
P356
10.1111/J.1538-7836.2010.04087.X
P577
2011-01-01T00:00:00Z