Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.
about
Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMAAberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy.Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing.Trinucleotide repeats and protein folding and disease: the perspective from studies with the androgen receptor.Targeted Molecular Therapies for SBMA.Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases.Ubiquitin-dependent and independent roles of SUMO in proteostasis.Post-translational Modifications and Protein Quality Control in Motor Neuron and Polyglutamine Diseases.Undoing SUMO aids polyQ AR.Fighting polyglutamine disease by wrestling with SUMO.The polyglutamine-expanded androgen receptor has increased DNA binding and reduced transcriptional activity.Sumoylation: Implications for Neurodegenerative Diseases.Transcriptional Dysregulation and Post-translational Modifications in Polyglutamine Diseases: From Pathogenesis to Potential Therapeutic Strategies.
P2860
Q30361988-19A79C32-0DCB-4E21-8593-6F16120E34C2Q36189002-93FC3DDC-18F1-444C-BA25-6C8E3CFB564BQ37361212-21015BCA-D31E-4494-B6F0-C3CAA2A8153EQ37474263-F288BB11-CD00-4D79-8148-0CEFE488114FQ38635851-878E310F-669E-4AE1-BA12-28FD4734AFF8Q38840491-6760C361-E034-49BF-A65C-A9007A551192Q38874015-C25EDDA6-7BE3-4E55-8DB6-FE1A7DFED297Q39241744-EFCAA4B8-7C1D-411B-A840-950098BD34CEQ42551916-A5DB98EA-642E-4A29-827E-C68918F04F69Q43135526-1A101EDA-1A21-48CA-B650-39C3CBFE2183Q47097766-D8DEFBF9-0113-49EF-8F2F-69FFEE815E0BQ47799714-DAE722A2-FF11-4EBC-98DC-064E3C9A26E8Q54965657-AE9DFCE8-277F-4E95-B745-08AA56774E75
P2860
Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Disrupting SUMOylation enhance ...... gen receptor-mediated disease.
@ast
Disrupting SUMOylation enhance ...... gen receptor-mediated disease.
@en
type
label
Disrupting SUMOylation enhance ...... gen receptor-mediated disease.
@ast
Disrupting SUMOylation enhance ...... gen receptor-mediated disease.
@en
prefLabel
Disrupting SUMOylation enhance ...... gen receptor-mediated disease.
@ast
Disrupting SUMOylation enhance ...... gen receptor-mediated disease.
@en
P2093
P2860
P356
P1476
Disrupting SUMOylation enhance ...... ogen receptor-mediated disease
@en
P2093
Andrew P Lieberman
Diane E Merry
Diane M Robins
Elisa Giorgetti
Heather L Montie
Jake Higgins
Jason P Chua
Richard C McEachin
Sarmistha Mukherjee
Satya L Reddy
P2860
P304
P356
10.1172/JCI73214
P407
P577
2015-01-20T00:00:00Z