Mass spectrometry-based proteomics of human cannabinoid receptor 2: covalent cysteine 6.47(257)-ligand interaction affording megagonist receptor activation.
about
Terpenes and lipids of the endocannabinoid and transient-receptor-potential-channel biosignaling systemsThe power of mass spectrometry in structural characterization of GPCR signaling.Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe.2012 Division of medicinal chemistry award address. Trekking the cannabinoid road: a personal perspectiveDesign and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 98(3.36) of the human histamine H₄ receptor.Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s).Virtual screening of CB(2) receptor agonists from bayesian network and high-throughput docking: structural insights into agonist-modulated GPCR features.Crystal Structure of the Human Cannabinoid Receptor CB1.Cannabinoids alleviate experimentally induced intestinal inflammation by acting at central and peripheral receptors.AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally restricted manner.3'-functionalized adamantyl cannabinoid receptor probes.Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor.In vitro and non-invasive in vivo effects of the cannabinoid-1 receptor agonist AM841 on gastrointestinal motor function in the rat.Synthesis and biological evaluation of indole-2-carboxamides bearing photoactivatable functionalities as novel allosteric modulators for the cannabinoid CB1 receptor.Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target.The future of drug discovery: enabling technologies for enhancing lead characterization and profiling therapeutic potential.Expression, Purification and Characterization of the Human Cannabinoid 1 Receptor.A clinically based protein discovery strategy to identify potential biomarkers of response to anti-TNF-α treatment of psoriatic arthritis.
P2860
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P2860
Mass spectrometry-based proteomics of human cannabinoid receptor 2: covalent cysteine 6.47(257)-ligand interaction affording megagonist receptor activation.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Mass spectrometry-based proteo ...... egagonist receptor activation.
@ast
Mass spectrometry-based proteo ...... egagonist receptor activation.
@en
type
label
Mass spectrometry-based proteo ...... egagonist receptor activation.
@ast
Mass spectrometry-based proteo ...... egagonist receptor activation.
@en
prefLabel
Mass spectrometry-based proteo ...... egagonist receptor activation.
@ast
Mass spectrometry-based proteo ...... egagonist receptor activation.
@en
P2093
P2860
P921
P356
P1476
Mass spectrometry-based proteo ...... egagonist receptor activation.
@en
P2093
Barry Karger
David R Janero
Dennis W Szymanski
Ganesh A Thakur
Katja Melchior
Malvina Papanastasiou
Richard W Mercier
Sangwon Cha
P2860
P304
P356
10.1021/PR2005583
P577
2011-09-13T00:00:00Z