Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect. - Wikidata - awgldk - TriplyDB

Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.

Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.

http://www.wikidata.org/entity/Q30412673

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Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans Increasing GLP-1 Circulating Levels by Bariatric Surgery or by GLP-1 Receptor Agonists Therapy: Why Are the Clinical Consequences so Different?Long-acting glucagon-like peptide-1 receptor agonists have direct access to and effects on pro-opiomelanocortin/cocaine- and amphetamine-stimulated transcript neurons in the mouse hypothalamus Neural control of energy balance: translating circuits to therapies Microbial regulation of GLP-1 and L-cell biology The glucagon-like peptide 1 receptor agonist liraglutide attenuates the reinforcing properties of alcohol in rodents Activation of murine pre-proglucagon-producing neurons reduces food intake and body weight.GLP-1R Signaling Directly Activates Arcuate Nucleus Kisspeptin Action in Brain Slices but Does not Rescue Luteinizing Hormone Inhibition in Ovariectomized Mice During Negative Energy Balance.Pharmacotherapy of Obesity: Clinical Trials to Clinical Practice.The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss.The GLP-1 agonist exendin-4 attenuates self-administration of sweetened fat on fixed and progressive ratio schedules of reinforcement in rats.Differences in acute anorectic effects of long-acting GLP-1 receptor agonists in rats.Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-cont Gut-brain mechanisms controlling glucose homeostasis.Liraglutide, leptin and their combined effects on feeding: additive intake reduction through common intracellular signalling mechanisms.GLP-1 based therapeutics: simultaneously combating T2DM and obesity.Lipoprotein effects of incretin analogs and dipeptidyl peptidase 4 inhibitors Efficacy and Clinical Characteristics of Liraglutide in Japanese Patients With Type 2 Diabetes.Brain GLP-1 and insulin sensitivity.Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer's Disease.Astrocytes Regulate GLP-1 Receptor-Mediated Effects on Energy Balance.Glucagon-Like Peptide-1 Receptor Activation in the Ventral Tegmental Area Decreases the Reinforcing Efficacy of Cocaine.Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study.Limiting glucocorticoid secretion increases the anorexigenic property of Exendin-4 Liraglutide prevents fast weight gain and β-cell dysfunction in male catch-up growth rats Extrapancreatic effects of incretin hormones: evidence for weight-independent changes in morphological aspects and oxidative status in insulin-sensitive organs of the obese nondiabetic Zucker rat (ZFR).Defining Conditions for Optimal Inhibition of Food Intake in Rats by a Grape-Seed Derived Proanthocyanidin Extract.Inhibition of glycine transporter-1 in the dorsal vagal complex improves metabolic homeostasis in diabetes and obesity.Disruption of Glucagon-Like Peptide 1 Signaling in Sim1 Neurons Reduces Physiological and Behavioral Reactivity to Acute and Chronic Stress.Albiglutide: a review of its use in patients with type 2 diabetes mellitus.Liraglutide for Type 2 diabetes and obesity: a 2015 update.Intestinal GLP-1 and satiation: from man to rodents and back.Mechanisms for the cardiovascular effects of glucagon-like peptide-1.Controlled release of biologics for the treatment of type 2 diabetes.Glucagon-like peptide-1 and glucagon-like peptide-1 receptor agonists in the treatment of type 2 diabetes.Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) in the Brain-Adipocyte Axis.Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight.Chronic intrahypothalamic rather than subcutaneous liraglutide treatment reduces body weight gain and stimulates the melanocortin receptor system.GLP-1 and weight loss: unraveling the diverse neural circuitry.

P2860

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P2860

Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.

http://www.wikidata.org/entity/Q30412673

description

2014 nî lūn-bûn

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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի ապրիլին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.

@ast

Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.

@en

type

label

Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.

@ast

Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.

@en

prefLabel

Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.

@ast

Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.

@en

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Journal of Clinical Investigation

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Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.

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P2093

Darleen A Sandoval

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David A D'Alessio

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Michael Scott

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Ruth Gutierrez-Aguilar

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Stephanie Sisley

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P2860

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness

Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons

Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch

Immuolocalization of nestin in pancreatic tissue of mice at different ages.

Effects of the once-daily GLP-1 analog liraglutide on gastric emptying, glycemic parameters, appetite and energy metabolism in obese, non-diabetic adults

Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism.

Assessment of feeding behavior in laboratory mice

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2456-2463

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scholarly article

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10.1172/JCI72434

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6

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124

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Randy J. Seeley

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2014-04-24T00:00:00Z

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261880764

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24762441

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4038572

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