Decreased neuraminidase activity is important for the adaptation of H5N1 influenza virus to human airway epithelium.
about
Use of ex vivo and in vitro cultures of the human respiratory tract to study the tropism and host responses of highly pathogenic avian influenza A (H5N1) and other influenza virusesMolecular basis for broad neuraminidase immunity: conserved epitopes in seasonal and pandemic H1N1 as well as H5N1 influenza virusesSelection on haemagglutinin imposes a bottleneck during mammalian transmission of reassortant H5N1 influenza virusesValidation of normal human bronchial epithelial cells as a model for influenza A infections in human distal tracheaCross-Reactive Neuraminidase-Inhibiting Antibodies Elicited by Immunization with Recombinant Neuraminidase Proteins of H5N1 and Pandemic H1N1 Influenza A Viruses.Single-domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge.Influenza A virus nucleoprotein selectively decreases neuraminidase gene-segment packaging while enhancing viral fitness and transmissibility.Immune escape mutants of Highly Pathogenic Avian Influenza H5N1 selected using polyclonal sera: identification of key amino acids in the HA proteinVaccine Design for H5N1 Based on B- and T-cell Epitope Predictions.Influenza B-cells protective epitope characterization: a passkey for the rational design of new broad-range anti-influenza vaccines.The universal epitope of influenza A viral neuraminidase fundamentally contributes to enzyme activity and viral replicationNovel Highly Pathogenic Avian A(H5N2) and A(H5N8) Influenza Viruses of Clade 2.3.4.4 from North America Have Limited Capacity for Replication and Transmission in Mammals.Viral and host factors required for avian H5N1 influenza A virus replication in mammalian cellsReduced susceptibility to all neuraminidase inhibitors of influenza H1N1 viruses with haemagglutinin mutations and mutations in non-conserved residues of the neuraminidase.Multiple introductions of highly pathogenic avian influenza H5N1 viruses into Bangladesh.Fitness costs for Influenza B viruses carrying neuraminidase inhibitor-resistant substitutions: underscoring the importance of E119A and H274Y.Recent biotechnological progress in enzymatic synthesis of glycosides.Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets.Genetic analysis of neuraminidase gene of influenza A(H1N1)pdm09 virus circulating in Southwest India from 2009 to 2012.Generation and characterization of interferon-lambda 1-resistant H1N1 influenza A viruses.How sticky should a virus be? The impact of virus binding and release on transmission fitness using influenza as an example.Ultrasensitive Fluorogenic Reagents for Neuraminidase Titration.Human bocavirus 1 infects commercially available primary human airway epithelium cultures productively.
P2860
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P2860
Decreased neuraminidase activity is important for the adaptation of H5N1 influenza virus to human airway epithelium.
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Decreased neuraminidase activi ...... us to human airway epithelium.
@ast
Decreased neuraminidase activi ...... us to human airway epithelium.
@en
type
label
Decreased neuraminidase activi ...... us to human airway epithelium.
@ast
Decreased neuraminidase activi ...... us to human airway epithelium.
@en
prefLabel
Decreased neuraminidase activi ...... us to human airway epithelium.
@ast
Decreased neuraminidase activi ...... us to human airway epithelium.
@en
P2860
P356
P1433
P1476
Decreased neuraminidase activi ...... us to human airway epithelium.
@en
P2093
Natalia A Ilyushina
Nicolai V Bovin
P2860
P304
P356
10.1128/JVI.06774-11
P577
2012-02-29T00:00:00Z