Identification of PTC725, an orally bioavailable small molecule that selectively targets the hepatitis C Virus NS4B protein
about
Identification of AP80978, a novel small-molecule inhibitor of hepatitis C virus replication that targets NS4B.Encoded library technology screening of hepatitis C virus NS4B yields a small-molecule compound series with in vitro replicon activity.Preclinical Characterization and In Vivo Efficacy of GSK8853, a Small-Molecule Inhibitor of the Hepatitis C Virus NS4B ProteinAntiviral Activity and Resistance Analysis of NS3/4A Protease Inhibitor Grazoprevir and NS5A Inhibitor Elbasvir in Hepatitis C Virus GT4 Replicons.PTC725, an NS4B-Targeting Compound, Inhibits a Hepatitis C Virus Genotype 3 Replicon, as Predicted by Genome Sequence Analysis and Determined ExperimentallyThe Combination of Grazoprevir, a Hepatitis C Virus (HCV) NS3/4A Protease Inhibitor, and Elbasvir, an HCV NS5A Inhibitor, Demonstrates a High Genetic Barrier to Resistance in HCV Genotype 1a Replicons.In vitro antiviral activity and preclinical and clinical resistance profile of miravirsen, a novel anti-hepatitis C virus therapeutic targeting the human factor miR-122.
P2860
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P2860
Identification of PTC725, an orally bioavailable small molecule that selectively targets the hepatitis C Virus NS4B protein
description
2013 nî lūn-bûn
@nan
2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Identification of PTC725, an o ...... hepatitis C Virus NS4B protein
@ast
Identification of PTC725, an o ...... hepatitis C Virus NS4B protein
@en
type
label
Identification of PTC725, an o ...... hepatitis C Virus NS4B protein
@ast
Identification of PTC725, an o ...... hepatitis C Virus NS4B protein
@en
prefLabel
Identification of PTC725, an o ...... hepatitis C Virus NS4B protein
@ast
Identification of PTC725, an o ...... hepatitis C Virus NS4B protein
@en
P2093
P2860
P356
P1476
Identification of PTC725, an o ...... hepatitis C Virus NS4B protein
@en
P2093
Amin Nomeir
James H Crona
Jamie J Breslin
Jason D Graci
Joseph M Colacino
Marla Weetall
Neil G Almstead
P2860
P304
P356
10.1128/AAC.00527-13
P407
P50
P577
2013-04-29T00:00:00Z