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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion SequencingAPOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcriptsBCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal CancerDevelopment of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolutionTracking genomic cancer evolution for precision medicine: the lung TRACERx studyDeciphering clonality in aneuploid breast tumors using SNP array and sequencing data.A genetic screen based on in vivo RNA imaging reveals centrosome-independent mechanisms for localizing gurken transcripts in DrosophilaSpatial and temporal diversity in genomic instability processes defines lung cancer evolution.Severe hypercholesterolemia in four British families with the D374Y mutation in the PCSK9 gene: long-term follow-up and treatment response.Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution.Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy.The origin, global distribution, and functional impact of the human 8p23 inversion polymorphism.Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencingCDKN2B expression in adipose tissue of familial combined hyperlipidemia patients.New technologies for delineating and characterizing the lipid exome: prospects for understanding familial combined hyperlipidemia.Small RNA profiling of Xenopus embryos reveals novel miRNAs and a new class of small RNAs derived from intronic transposable elements.Prognostic impact of p62 expression in cutaneous malignant melanomaCancer heterogeneity and "the struggle for existence": diagnostic and analytical challenges.Mutation of cancer driver MLL2 results in transcription stress and genome instability.Tracking the Evolution of Non-Small-Cell Lung Cancer.SRF Co-factors Control the Balance between Cell Proliferation and Contractility.Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts.ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with TranscriptionAPC/C Dysfunction Limits Excessive Cancer Chromosomal Instability.Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis.Acute myeloid leukemia xenograft success prediction: Saving time.Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.Detection of ubiquitous and heterogeneous mutations in cell-free DNA from patients with early-stage non-small-cell lung cancer.Overlapping BXSB congenic intervals, in combination with microarray gene expression, reveal novel lupus candidate genesThe Wilms Tumor-1 (WT1) rs2234593 variant is a prognostic factor in normal karyotype acute myeloid leukemiaDevelopment of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer
P50
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P50
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hulumtues
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հետազոտող
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Stuart Horswell
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Stuart Horswell
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Stuart Horswell
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Stuart Horswell
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Stuart Horswell
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Stuart Horswell
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Stuart Horswell
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Stuart Horswell
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Stuart Horswell
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Stuart Horswell
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Stuart Horswell
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Stuart Horswell
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Stuart Horswell
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P108
P106
P21
P31
P496
0000-0003-2787-1933