SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML) - Wikidata - awgldk - TriplyDB

SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

http://www.wikidata.org/entity/Q30420638

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Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis Therapeutic approaches in myelofibrosis and myelodysplastic/myeloproliferative overlap syndromes Cytogenetic and molecular abnormalities in chronic myelomonocytic leukemia Functions of TET Proteins in Hematopoietic Transformation Connections between TET proteins and aberrant DNA modification in cancer MDS prognostic scoring systems – past, present, and future MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance Atypical chronic myeloid leukemia is clinically distinct from unclassifiable myelodysplastic/myeloproliferative neoplasms.Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia.GM-CSF-dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia.Myelodysplastic syndromes: diagnosis, prognosis, and treatment.Molecular genetics of chronic neutrophilic leukemia, chronic myelomonocytic leukemia and atypical chronic myeloid leukemia.Detection of SRSF2-P95 mutation by high-resolution melting curve analysis and its effect on prognosis in myelodysplastic syndrome.Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome.Impact of TET2, SRSF2, ASXL1 and SETBP1 mutations on survival of patients with chronic myelomonocytic leukemia An international data set for CMML validates prognostic scoring systems and demonstrates a need for novel prognostication strategies.Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia.Mastocytosis: a mutated KIT receptor induced myeloproliferative disorder Molecular analyses of 15,542 patients with suspected BCR-ABL1-negative myeloproliferative disorders allow to develop a stepwise diagnostic workflow.IDH1 and IDH2 mutations in myelodysplastic syndromes and role in disease progression Prognostic interaction between ASXL1 and TET2 mutations in chronic myelomonocytic leukemia An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms.Chronic myelomonocytic leukemia: Forefront of the field in 2015.Myeloid neoplasms with isolated isochromosome 17q demonstrate a high frequency of mutations in SETBP1, SRSF2, ASXL1 and NRAS.Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms.Routine clinical mutation profiling using next generation sequencing and a customized gene panel improves diagnostic precision in myeloid neoplasms.Clinical management of myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes.Age-related mutations and chronic myelomonocytic leukemia.Acquired ASXL1 mutations are common in patients with inherited GATA2 mutations and correlate with myeloid transformation.Targeted deep sequencing improves outcome stratification in chronic myelomonocytic leukemia with low risk cytogenetic features.Splicing factor mutations in myelodysplasia.Next-generation sequencing - feasibility and practicality in haematology.Spliceosome mutations in myelodysplastic syndromes and chronic myelomonocytic leukemia.Regulation of splicing by SR proteins and SR protein-specific kinases.An evolutionary perspective on chronic myelomonocytic leukemia.Recent advances in understanding the molecular pathogenesis of myelodysplastic syndromes.Management recommendations for chronic myelomonocytic leukemia: consensus statements from the SIE, SIES, GITMO groups Splicing factor mutations and cancer.Chronic myelomonocytic leukemia prognostic classification and management: evidence base and current practice.Molecular pathogenesis of atypical CML, CMML and MDS/MPN-unclassifiable.

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SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

http://www.wikidata.org/entity/Q30420638

description

2012 nî lūn-bûn

@nan

2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի օգոստոսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

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SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

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type

label

SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

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SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

@en

prefLabel

SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

@ast

SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

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BLOOD-2012-01-404863

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SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

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Alexander Kohlmann

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Andreas Roller

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Christiane Eder

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Frank Dicker

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H Phillip Koeffler

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Seishi Ogawa

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Vera Grossmann

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Wolfgang Kern

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Initial sequencing and analysis of the human genome

The SR protein family

EUKARYOTIC CYTOSINE METHYLTRANSFERASES

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

SR proteins in vertical integration of gene expression from transcription to RNA processing to translation

Discovery of novel splice forms and functional analysis of cancer-specific alternative splicing in human expressed sequences

Asyn-anticonformational difference allows SRSF2 to recognize guanines and cytosines equally well

TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs).

Protein structure comparison by alignment of distance matrices

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3080-3088

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scholarly article

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10.1182/BLOOD-2012-01-404863

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120

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Kenichi Yoshida

Torsten Haferlach

Tamara Alpermann

Manja Meggendorfer

Claudia Haferlach

Susanne Schnittger

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2012-08-23T00:00:00Z

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230733826

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22919025

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3580040

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