Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
about
Holoprosencephaly: signaling interactions between the brain and the face, the environment and the genes, and the phenotypic variability in animal models and humansTALE transcription factors during early development of the vertebrate brain and eyeTGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesisTGFβ signalling in contextPremature senescence and increased TGFβ signaling in the absence of Tgif1.Tgif disruption of Shh signalingTgif1 and Tgif2 Repress Expression of the RabGAP Evi5l.Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning.Tgif1 and Tgif2 Regulate Axial Patterning in Mouse.Tgif1 regulates quiescence and self-renewal of hematopoietic stem cellsProstate cancer induced by loss of Apc is restrained by TGFβ signalingOtitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development.Meeting the challenge of interpreting high-resolution single nucleotide polymorphism array data in prenatal diagnosis: does increased diagnostic power outweigh the dilemma of rare variants?The ubiquitin E3 ligase NOSIP modulates protein phosphatase 2A activity in craniofacial development.Genetic similarity between cancers and comorbid Mendelian diseases identifies candidate driver genes.Prenatal Diagnosis of Central Nervous System Anomalies by High-Resolution Chromosomal Microarray Analysis.The human brain and face: mechanisms of cranial, neurological and facial development revealed through malformations of holoprosencephaly, cyclopia and aberrations in chromosome 18ProNodal acts via FGFR3 to govern duration of Shh expression in the prechordal mesodermRescue of holoprosencephaly in fetal alcohol-exposed Cdon mutant mice by reduced gene dosage of Ptch1.A prenatal missed diagnosed case of submicroscopic chromosomal abnormalities by karyotyping: the clinical utility of array-based CGH in prenatal diagnostics.Glimpse into Hox and tale regulation of cell differentiation and reprogramming.Hedgehog: Multiple Paths for Multiple Roles in Shaping the Brain and Spinal Cord.Fryns Syndrome Associated with Recessive Mutations in PIGN in two Separate Families.The TG-interacting factor TGIF1 regulates stress-induced proinflammatory phenotype of endothelial cellsTGFβ induced factor homeobox 1 promotes colorectal cancer development through activating Wnt/β-catenin signaling.Link between the causative genes of holoprosencephaly: Zic2 directly regulates Tgif1 expression.A boy with partial dup(18q)/del(18p) due to a maternal pericentric inversion: Genotype-phenotype correlation and risk of recombinant chromosomes based on systematic review of the literature.Genotypic and phenotypic variation in six patients with solitary median maxillary central incisor syndrome.Silencing of TGIF1 in bone mesenchymal stem cells applied to the post-operative rotator cuff improves both functional and histologic outcomes.Functions of TGIF homeodomain proteins and their roles in normal brain development and holoprosencephaly
P2860
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P2860
Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
@ast
Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
@en
type
label
Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
@ast
Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
@en
prefLabel
Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
@ast
Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
@en
P2860
P1433
P1476
Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
@en
P2093
Anoush E Anderson
Kenichiro Taniguchi
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002524
P577
2012-02-23T00:00:00Z