Increased acid stability of the hemagglutinin protein enhances H5N1 influenza virus growth in the upper respiratory tract but is insufficient for transmission in ferrets.
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Transmission of influenza A virusesFusion of Enveloped Viruses in Endosomes.One health, multiple challenges: The inter-species transmission of influenza A virusMolecular requirements for a pandemic influenza virus: An acid-stable hemagglutinin proteinAirborne transmission of highly pathogenic H7N1 influenza virus in ferretsInfluenza A virus transmission via respiratory aerosols or droplets as it relates to pandemic potentialAvian influenza A viruses: from zoonosis to pandemicHost adaptation and transmission of influenza A viruses in mammalsMammalian adaptation of influenza A(H7N9) virus is limited by a narrow genetic bottleneck.Viral factors in influenza pandemic risk assessment.The matrix gene segment destabilizes the acid and thermal stability of the hemagglutinin of pandemic live attenuated influenza virus vaccinesMutations to PB2 and NP proteins of an avian influenza virus combine to confer efficient growth in primary human respiratory cells.Characterization of H5N1 influenza virus variants with hemagglutinin mutations isolated from patientsH1N1 Swine Influenza Viruses Differ from Avian Precursors by a Higher pH Optimum of Membrane Fusion.H1N1 influenza viruses varying widely in hemagglutinin stability transmit efficiently from swine to swine and to ferrets.pH Optimum of Hemagglutinin-Mediated Membrane Fusion Determines Sensitivity of Influenza A Viruses to the Interferon-Induced Antiviral State and IFITMs.Human-Animal Interface: The Case for Influenza Interspecies Transmission.Molecular mechanism of the airborne transmissibility of H9N2 avian influenza A viruses in chickens.Role of receptor binding specificity in influenza A virus transmission and pathogenesis.Identification, characterization, and natural selection of mutations driving airborne transmission of A/H5N1 virus.A recommended numbering scheme for influenza A HA subtypesAnimal models for influenza virus transmission studies: a historical perspective.Novel Highly Pathogenic Avian A(H5N2) and A(H5N8) Influenza Viruses of Clade 2.3.4.4 from North America Have Limited Capacity for Replication and Transmission in Mammals.Novel H7N9 influenza virus shows low infectious dose, high growth rate, and efficient contact transmission in the guinea pig modelInfluenza Virus Overcomes Cellular Blocks To Productively Replicate, Impacting Macrophage FunctionMutations Driving Airborne Transmission of A/H5N1 Virus in Mammals Cause Substantial Attenuation in Chickens only when combined.Amino Acid Substitutions That Affect Receptor Binding and Stability of the Hemagglutinin of Influenza A/H7N9 Virus.Modulation of the pH Stability of Influenza Virus Hemagglutinin: A Host Cell Adaptation Strategy.The Interplay between the Host Receptor and Influenza Virus Hemagglutinin and Neuraminidase.Evolution of Influenza A Virus by Mutation and Re-Assortment.A histidine residue of the influenza virus hemagglutinin controls the pH dependence of the conformational change mediating membrane fusion.Modulating secretory pathway pH by proton channel co-expression can increase recombinant protein stability in plants.Sequence changes associated with respiratory transmission of H7N1 influenza virus in mammals.Human Clade 2.3.4.4 A/H5N6 Influenza Virus Lacks Mammalian Adaptation Markers and Does Not Transmit via the Airborne Route between Ferrets.Impact of Mutations in the Hemagglutinin of H10N7 Viruses Isolated from Seals on Virus Replication in Avian and Human Cells.Influenza Hemagglutinin Protein Stability, Activation, and Pandemic Risk.The Pandemic Threat of Emerging H5 and H7 Avian Influenza VirusesA Dual Motif in the Hemagglutinin of H5N1 Goose/Guangdong-Like Highly Pathogenic Avian Influenza Virus Strains Is Conserved from Their Early Evolution and Increases both Membrane Fusion pH and VirulenceStochastic Model of Acidification, Activation of Hemagglutinin and Escape of Influenza Viruses from an Endosome
P2860
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P2860
Increased acid stability of the hemagglutinin protein enhances H5N1 influenza virus growth in the upper respiratory tract but is insufficient for transmission in ferrets.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Increased acid stability of th ...... t for transmission in ferrets.
@ast
Increased acid stability of th ...... t for transmission in ferrets.
@en
type
label
Increased acid stability of th ...... t for transmission in ferrets.
@ast
Increased acid stability of th ...... t for transmission in ferrets.
@en
prefLabel
Increased acid stability of th ...... t for transmission in ferrets.
@ast
Increased acid stability of th ...... t for transmission in ferrets.
@en
P2093
P2860
P50
P356
P1433
P1476
Increased acid stability of th ...... t for transmission in ferrets.
@en
P2093
Charles J Russell
Mark L Reed
Olga A Bridges
Rachelle Salomon
Sun-Woo Yoon
Tatiana Baranovich
P2860
P304
P356
10.1128/JVI.01175-13
P577
2013-07-03T00:00:00Z