Sphingosine 1-phosphate analogs as receptor antagonists.
about
Sphingolipids: a potential molecular approach to treat allergic inflammationCrystal structure of a lipid G protein-coupled receptorFTY720 story. Its discovery and the following accelerated development of sphingosine 1-phosphate receptor agonists as immunomodulators based on reverse pharmacologyRoles of bioactive sphingolipids in cancer biology and therapeuticsIntegrating the puzzle pieces: the current atomistic picture of phospholipid-G protein coupled receptor interactionsSphingosine kinase and sphingosine 1-phosphate in the heart: a decade of progressSphingosine-1-Phosphate Receptor-1 Selective Agonist Enhances Collateral Growth and Protects against Subsequent StrokeRegulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphateIntracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyaseEngineering in vivo gradients of sphingosine-1-phosphate receptor ligands for localized microvascular remodeling and inflammatory cell positioningSphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors.Characterization of a sphingosine 1-phosphate receptor antagonist prodrugSphingosine 1-phosphate chemical biologyInternational Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature.Activation of sphingosine-1-phosphate 1 receptor in the proximal tubule protects against ischemia-reperfusion injury.Synthesis and biological evaluation of sphingosine kinase substrates as sphingosine-1-phosphate receptor prodrugs.Asymmetric synthesis of conformationally constrained fingolimod analogues--discovery of an orally active sphingosine 1-phosphate receptor type-1 agonist and receptor type-3 antagonist.Sphingosine-1-phosphate inhibits high glucose-mediated ERK1/2 action in endothelium through induction of MAP kinase phosphatase-3.Sphingosine-1-phosphate receptors: biology and therapeutic potential in kidney diseaseSphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype.Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists.Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cellsB lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis.A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis.Sphingosine kinase and sphingosine 1-phosphate in cardioprotection.Cardiomyocyte S1P1 receptor-mediated extracellular signal-related kinase signaling and desensitizationHigh-density lipoprotein determines adult mouse cardiomyocyte fate after hypoxia-reoxygenation through lipoprotein-associated sphingosine 1-phosphate.Isoflurane protects human kidney proximal tubule cells against necrosis via sphingosine kinase and sphingosine-1-phosphate generationSphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice.Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6An update on the biology of sphingosine 1-phosphate receptors.Lysophospholipid receptor nomenclature review: IUPHAR Review 8.Isoflurane posttreatment reduces neonatal hypoxic-ischemic brain injury in rats by the sphingosine-1-phosphate/phosphatidylinositol-3-kinase/Akt pathway.Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway.Sphingosine-1-phosphate prevents permeability increases via activation of endothelial sphingosine-1-phosphate receptor 1 in rat venules.Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond.Sphingosine-1-phosphate and immune regulation: trafficking and beyondThe interaction between C5a and sphingosine-1-phosphate in neutrophils for antineutrophil cytoplasmic antibody mediated activation.
P2860
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P2860
Sphingosine 1-phosphate analogs as receptor antagonists.
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Sphingosine 1-phosphate analogs as receptor antagonists.
@ast
Sphingosine 1-phosphate analogs as receptor antagonists.
@en
type
label
Sphingosine 1-phosphate analogs as receptor antagonists.
@ast
Sphingosine 1-phosphate analogs as receptor antagonists.
@en
prefLabel
Sphingosine 1-phosphate analogs as receptor antagonists.
@ast
Sphingosine 1-phosphate analogs as receptor antagonists.
@en
P2093
P356
P1476
Sphingosine 1-phosphate analogs as receptor antagonists.
@en
P2093
Jeremy J Clemens
Kevin R Lynch
Michael D Davis
Timothy L Macdonald
P304
P356
10.1074/JBC.M412356200
P407
P577
2004-12-08T00:00:00Z