An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells.
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HDL and glucose metabolism: current evidence and therapeutic potentialThe role of cholesterol in membrane fusionLoss of ABCG1 influences regulatory T cell differentiation and atherosclerosis.Nuclear receptors as drug targets for metabolic disease.Cholesterol accumulation increases insulin granule size and impairs membrane trafficking.Lipoproteins and β-Cell Functions: From Basic to Clinical Data.ABCG1 as a potential oncogene in lung cancerRegulation of ABCG1 expression in human keratinocytes and murine epidermis.Retinal and nonocular abnormalities in Cyp27a1(-/-)Cyp46a1(-/-) mice with dysfunctional metabolism of cholesterol.ABCG1 is required for pulmonary B-1 B cell and natural antibody homeostasis.Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell.Cellular Localization and Trafficking of the Human ABCG1 TransporterThe Human ABCG1 Transporter Mobilizes Plasma Membrane and Late Endosomal Non-Sphingomyelin-Associated-Cholesterol for Efflux and Esterification.Effect of apoA-I Mutations in the Capacity of Reconstituted HDL to Promote ABCG1-Mediated Cholesterol Efflux.Type 2 diabetes is associated with reduced ATP-binding cassette transporter A1 gene expression, protein and functionThe cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity.Characterization of phospholipids in insulin secretory granules and mitochondria in pancreatic beta cells and their changes with glucose stimulation.Islet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules.ATP binding cassette transporter G1 (ABCG1) is an intracellular sterol transporter.Association between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 StudyAdipose ABCG1: A potential therapeutic target in obesity?ABCG1 regulates mouse adipose tissue macrophage cholesterol levels and ratio of M1 to M2 cells in obesity and caloric restrictionABC transporter genes and risk of type 2 diabetes: a study of 40,000 individuals from the general population.Restoring Mitochondrial Function: A Small Molecule-mediated Approach to Enhance Glucose Stimulated Insulin Secretion in Cholesterol Accumulated Pancreatic beta cellsATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell developmentChanges in triglycerides and high-density lipoprotein cholesterol may precede peripheral insulin resistance, with 2-h insulin partially mediating this unidirectional relationship: a prospective cohort study.The ATP binding cassette transporter, ABCG1, localizes to cortical actin filaments.Epigenome-wide association study of fasting measures of glucose, insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network study.The emerging role of HDL in glucose metabolism.Influence of cholesterol on cellular signaling and fusion pore kinetics.Genetics of cholesterol efflux.ATP-binding cassette transporters and cholesterol translocation.ATP-binding cassette transporters and cholesterol translocation.Cholesterol-enriched membrane rafts and insulin secretion.High-density lipoprotein, beta cells, and diabetes .ApoA-I/HDL Generation and Intracellular Cholesterol Transport through Cytosolic Lipid-Protein Particles in Astrocytes.The diabetogenic action of statins - mechanisms and clinical implications.Intracellular Localization of Endogenous Mouse ABCG1 Is Mimicked by Both ABCG1-L550 and ABCG1-P550-Brief Report.Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function.Critical Role of the Human ATP-Binding Cassette G1 Transporter in Cardiometabolic Diseases.
P2860
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P2860
An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells.
description
2010 nî lūn-bûn
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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
An intracellular role for ABCG ...... f mouse pancreatic beta cells.
@ast
An intracellular role for ABCG ...... f mouse pancreatic beta cells.
@en
type
label
An intracellular role for ABCG ...... f mouse pancreatic beta cells.
@ast
An intracellular role for ABCG ...... f mouse pancreatic beta cells.
@en
prefLabel
An intracellular role for ABCG ...... f mouse pancreatic beta cells.
@ast
An intracellular role for ABCG ...... f mouse pancreatic beta cells.
@en
P2093
P2860
P356
P1476
An intracellular role for ABCG ...... f mouse pancreatic beta cells.
@en
P2093
Anna M Castle
Anthony P Trace
Catherine C Hedrick
J David Castle
Jeffrey M Sturek
John S Parks
Laura C Page
Raghavendra G Mirmira
P2860
P304
P356
10.1172/JCI41280
P407
P577
2010-06-07T00:00:00Z