Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea - Wikidata - awgldk - TriplyDB

Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea

Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea

http://www.wikidata.org/entity/Q30435999

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Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15.TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells.The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse The small GTPase Rac1 regulates auditory hair cell morphogenesis.Characterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factor HCN channels are not required for mechanotransduction in sensory hair cells of the mouse inner ear.Two-Dimensional Cochlear Micromechanics Measured In Vivo Demonstrate Radial Tuning within the Mouse Organ of Corti.Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing.Quantitative High-Resolution Cellular Map of the Organ of Corti.Relating structure and function of inner hair cell ribbon synapses.The physiology of mechanoelectrical transduction channels in hearing.Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo Retinoic acid signalling regulates the development of tonotopically patterned hair cells in the chicken cochlea TMC function in hair cell transduction Functional contributions of HCN channels in the primary auditory neurons of the mouse inner ear.The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative gene Kif3a regulates planar polarization of auditory hair cells through both ciliary and non-ciliary mechanisms.Polycystin-1 is required for stereocilia structure but not for mechanotransduction in inner ear hair cells.A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.Developmental changes in the cochlear hair cell mechanotransducer channel and their regulation by transmembrane channel-like proteins.Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells Gene expression gradients along the tonotopic axis of the chicken auditory epithelium Gradients and modulation of K(+) channels optimize temporal accuracy in networks of auditory neurons.Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia.Roles of the espin actin-bundling proteins in the morphogenesis and stabilization of hair cell stereocilia revealed in CBA/CaJ congenic jerker mice.Kinocilia mediate mechanosensitivity in developing zebrafish hair cells.Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells.Absence of plastin 1 causes abnormal maintenance of hair cell stereocilia and a moderate form of hearing loss in mice.Mechanosensory hair cells express two molecularly distinct mechanotransduction channels.Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells.Failure of fluid absorption in the endolymphatic sac initiates cochlear enlargement that leads to deafness in mice lacking pendrin expression.Preliminary characterization of voltage-activated whole-cell currents in developing human vestibular hair cells and calyx afferent terminals.Developmental gene expression profiling along the tonotopic axis of the mouse cochlea.Generation of Atoh1-rtTA transgenic mice: a tool for inducible gene expression in hair cells of the inner ear Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c.Endolymphatic Na⁺ and K⁺ concentrations during cochlear growth and enlargement in mice lacking Slc26a4/pendrin.

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P2860

Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea

http://www.wikidata.org/entity/Q30435999

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2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Tonotopic gradient in the deve ...... air cells of the mouse cochlea

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Tonotopic gradient in the deve ...... air cells of the mouse cochlea

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Journal of Neurophysiology

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Tonotopic gradient in the deve ...... air cells of the mouse cochlea

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P2093

Andrea Lelli

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Andrew Forge

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Gwenaëlle S G Géléoc

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Jeffrey R Holt

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Yukako Asai

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P2860

A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness

From flies' eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30

A new compartment at stereocilia tips defined by spatial and temporal patterns of myosin IIIa expression

Defective myosin VIIA gene responsible for Usher syndrome type 1B

Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B

Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia

Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2

The autosomal recessive isolated deafness, DFNB2, and the Usher 1B syndrome are allelic defects of the myosin-VIIA gene

Ames Waltzer deaf mice have reduced electroretinogram amplitudes and complex alternative splicing of Pcdh15 transcripts

Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development

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10.1152/JN.00136.2009

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6

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101

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19339464

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2694104

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