Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia.
about
RhoGDI2 suppresses lung metastasis in mice by reducing tumor versican expression and macrophage infiltration.Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function.Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin SNovel role of the anorexigenic peptide neuromedin U in the control of LH secretion and its regulation by gonadal hormones and photoperiodIdentification of non-peptidic neuromedin U receptor modulators by a robust homogeneous screening assayLoss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor αCD24 offers a therapeutic target for control of bladder cancer metastasis based on a requirement for lung colonization.The Ral GTPase pathway in metastatic bladder cancer: key mediator and therapeutic targetTranslation initiation factor eIF3b expression in human cancer and its role in tumor growth and lung colonizationCD24 is an effector of HIF-1-driven primary tumor growth and metastasis.A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness.Phosphorylation of RalB is important for bladder cancer cell growth and metastasisRhoGDI3 and RhoG: Vesicular trafficking and interactions with the Sec3 Exocyst subunit.RalBP1 is necessary for metastasis of human cancer cell linesLearning therapeutic lessons from metastasis suppressor proteins.A voting approach to identify a small number of highly predictive genes using multiple classifiers.Oncogenic features of neuromedin U in breast cancer are associated with NMUR2 expression involving crosstalk with members of the WNT signaling pathway.A new tumour suppression mechanism by p27Kip1: EGFR down-regulation mediated by JNK/c-Jun pathway inhibition.Small lipidated anti-obesity compounds derived from neuromedin U.Identifying a Neuromedin U Receptor 2 Splice Variant and Determining Its Roles in the Regulation of Signaling and Tumorigenesis In Vitro.Identification of genetic variations of a Chinese family with paramyotonia congenita via whole exome sequencing.Metastasis suppressors and their roles in breast carcinoma.NMU signaling promotes endometrial cancer cell progression by modulating adhesion signaling.Overexpression of neuromedin U is correlated with regional metastasis of head and neck squamous cell carcinoma.RhoGDI2 as a therapeutic target in cancer.Genetics of breast cancer bone metastasis: a sequential multistep pattern.Prognostic value of Rho GDP dissociation inhibitors in patients with hepatocellular carcinoma following liver transplantationInactivation of the von Hippel-Lindau tumour suppressor gene induces Neuromedin U expression in renal cancer cells.Systematic Review: Characteristics and Preclinical Uses of Bladder Cancer Cell Lines.
P2860
Q24608385-B49CC777-DF7C-4947-A0AD-BBB1D1529962Q24645336-BE5A75D2-06F6-444B-8F6C-9B540603D700Q24656469-957744E4-B339-44C4-A904-570BB9DCC5E6Q28242546-0572469A-D2CA-456D-B23D-D0E332E82EA0Q28273552-CB2A69D6-5CC3-4F77-B6A6-19ACFBD7F340Q28308069-312E3F1F-682E-4DE3-95A9-19EA7971D337Q30408689-83146626-31F5-46D1-B705-8E0CEF28CD9EQ30415154-46B8EF13-2F8B-4AFC-98BF-753BC32DA3F2Q30416020-CA6A2B3B-D9DE-4744-A8D8-D2F6C095BBC6Q30416514-BFB0B26A-93D7-4F87-9B71-2DA4D0F60926Q30422907-EC32D204-C423-4A1B-A345-027A5D34822FQ30429890-85EBAAEB-8C7A-4F0C-9BA8-8AAA6D859B90Q30431874-AA22F362-5A76-4CEF-BA1C-CA9847354A01Q30433862-0BB25D44-F5E7-4A0F-8F6A-450DBA4355AEQ30435922-FF7AA481-6CD5-4DC8-952A-BF65C551ABEDQ33407768-52CF75D7-ABE0-4F23-A955-A7644CE48813Q33829465-C3E8FB1E-2931-4B0E-8E7A-A36612DFBE9EQ34406424-FFEEB6E0-2E2A-49B0-A00E-7B0F8FB3A007Q35708420-225F5B0E-2520-4833-86E5-73B23E4D8854Q35758543-477B0E05-E911-46D1-AF27-BB76DE7451F0Q35951487-6D011C36-F307-4F18-BE2B-E2A598F20087Q35981102-DCCB01A3-F0FC-49DE-9E7B-5202469C44A1Q36962930-943F110E-C5F2-40FB-9861-C4288DADEC7FQ37082967-BAE111FE-3C22-423E-A372-E9BE197E59E5Q37650185-76B5148D-7097-406E-BBD7-78E944C35C91Q38184928-3B3F301C-A4BF-4281-A85A-DD00154FD5E0Q38695493-95830003-3EEA-4BFC-A2CB-422229A97E3CQ39500622-1D416AB0-2A84-4440-87AE-F279257D658CQ55397522-A77A7693-96E5-43CB-90E4-A8832FBC2028
P2860
Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Neuromedin U is regulated by t ...... etastasis and cancer cachexia.
@ast
Neuromedin U is regulated by t ...... etastasis and cancer cachexia.
@en
type
label
Neuromedin U is regulated by t ...... etastasis and cancer cachexia.
@ast
Neuromedin U is regulated by t ...... etastasis and cancer cachexia.
@en
prefLabel
Neuromedin U is regulated by t ...... etastasis and cancer cachexia.
@ast
Neuromedin U is regulated by t ...... etastasis and cancer cachexia.
@en
P2093
P2860
P356
P1433
P1476
Neuromedin U is regulated by t ...... etastasis and cancer cachexia.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1209835
P407
P577
2006-07-31T00:00:00Z
P5875
P6179
1033383880