Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis. - Wikidata - awgldk - TriplyDB

Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis.

Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis.

http://www.wikidata.org/entity/Q30442993

about

Pak1 and Pak2 are activated in recurrent respiratory papillomas, contributing to one pathway of Rac1-mediated COX-2 expression Regulated Hyaluronan Synthesis by Vascular Cells PAK signalling during the development and progression of cancer Altered nitric oxide production mediates matrix-specific PAK2 and NF-κB activation by flow A role for a CXCR2/phosphatidylinositol 3-kinase gamma signaling axis in acute and chronic vascular permeability.p21-activated kinase 1 participates in vascular remodeling in vitro and in vivo 3D structure analysis of PAKs: A clue to the rational design for affinity reagents and blockers.Polarized actin structural dynamics in response to cyclic uniaxial stretch.Flow-dependent cellular mechanotransduction in atherosclerosis.Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells.The role of p21-activated kinase in the initiation of atherosclerosis.Hemodynamic activation of beta-catenin and T-cell-specific transcription factor signaling in vascular endothelium regulates fibronectin expression.Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation Matrix-specific protein kinase A signaling regulates p21-activated kinase activation by flow in endothelial cells Focal adhesion kinase modulates activation of NF-kappaB by flow in endothelial cells.PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns The subendothelial extracellular matrix modulates JNK activation by flow Cell adhesion receptors in mechanotransduction The role of cellular adaptation to mechanical forces in atherosclerosis.Mechanotransduction in vascular physiology and atherogenesis.p21-activated kinase signaling regulates oxidant-dependent NF-kappa B activation by flow.Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells.Cytosolic SYT/SS18 isoforms are actin-associated proteins that function in matrix-specific adhesion.The arterial microenvironment: the where and why of atherosclerosis.α5β1 integrin signaling mediates oxidized low-density lipoprotein-induced inflammation and early atherosclerosis.Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives KRIT1 protein depletion modifies endothelial cell behavior via increased vascular endothelial growth factor (VEGF) signaling.Twist1 controls lung vascular permeability and endotoxin-induced pulmonary edema by altering Tie2 expression.PAK1 as a therapeutic target.Recruitment of the adaptor protein Nck to PECAM-1 couples oxidative stress to canonical NF-κB signaling and inflammation.p21-Activated kinase 3 (PAK3) protein regulates synaptic transmission through its interaction with the Nck2/Grb4 protein adaptor Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes.Adaptive response of vascular endothelial cells to an acute increase in shear stress magnitude Flow mechanotransduction regulates traction forces, intercellular forces, and adherens junctions LDL-Cholesterol Increases the Transcytosis of Molecules through Endothelial Monolayers Transactivation of vascular endothelial growth factor receptor-2 by interleukin-8 (IL-8/CXCL8) is required for IL-8/CXCL8-induced endothelial permeability.HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1 to limit vascular inflammation.Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation.TGFβ receptor I transactivation mediates stretch-induced Pak1 activation and CTGF upregulation in mesangial cells

P2860

Q24619064-FFA636C1-CE63-4D62-A9BD-D83D3590884B Q26786080-1674F1C8-89C3-4992-87FD-441DCAD6AEE7 Q28307460-979CF252-0491-4CFD-86AB-92A3EBDB186E Q28394043-8AFE167A-E684-43C1-8C61-3829AB2526DE Q28566820-52DD8511-5072-4ACE-A09C-F24E8B995DF1 Q28570035-7B867FF9-C7BD-41A0-8D8D-35C4D0BB6AE7 Q30009979-8BB44E8A-3A2A-49FA-BE1B-3375855E1BBD Q30300280-BDFA81F6-4F5F-49A9-90B1-A53F33E85810 Q30409536-0BED4B22-927D-437A-8E80-3472F2442153 Q30411892-D2001F36-15E0-41E1-A6B5-CAB685714486 Q30424082-5C235577-33F1-4659-B49F-3B3E1E39D8DD Q30426148-F44CC18A-757B-42C3-BFF7-F2FC55977CF3 Q30431932-5A450B3F-94B6-4EDE-A446-FA66E821C822 Q30432582-02A0E433-2895-4C21-BAC2-8D211E0E22D4 Q30434583-7702B44B-3F09-4896-ABED-55483E6F82AB Q30437153-4DCE6906-9358-4D05-B87E-B802FAE8FAB1 Q30438150-5B88799F-DD00-4352-BE31-4B1FC16CA9FB Q30438289-30828A91-D50D-4560-9F96-D8678B4F3A13 Q30438718-417A49F6-8E5F-4166-AB82-176055F41C98 Q30439086-FD39F348-B101-4550-B9F5-FCCEEF4EA8FD Q30439404-A09DCE31-D7C7-43FB-A96A-82D8A8426030 Q30530606-150BC790-4FF2-4F82-AF9B-B985F5FA7571 Q33489583-DFAF8D31-934D-4E28-9544-C8CC279444CD Q33619657-6CC29203-A722-46FF-9AF5-599313B7CB11 Q33896730-528F0E8A-EF29-4CA0-9243-2DB12311A54F Q34159834-4DCA11F7-B07B-4B36-A622-97F1E078B5EA Q34552843-65C92C0E-B9A7-4733-A5AF-27BA9151ADEA Q34984424-C19CF5AF-B297-41FC-896B-DE59E3D8270A Q35108164-A065028B-4EC9-40CA-9CBB-A378E99203B2 Q35551178-0FE4B9D2-0492-41AB-B8B3-C3C548211F47 Q35562644-CBE4D192-594B-478C-BA05-5AB5106089E0 Q35780426-24D298ED-B995-44AA-9C77-FE8CD4C17B9A Q35830289-806EA325-BFE0-420D-B6FE-60856C55EFC5 Q35879188-F97F9821-4256-4545-9C57-DA3990217707 Q36042619-554825CC-6E02-494D-A3D2-F110791D64D6 Q36151006-7FC74440-FF5F-40E6-AF03-915310DF293A Q36173954-01DC8756-289D-44E7-9C4F-0B3B5E842CE6 Q36623447-EF6BE4CA-056A-420C-A3D2-C7CF3F7FF22A Q36749619-6D54176E-7CE3-4441-B2B2-55B3B328868C Q37096498-F30592EE-F171-4FFF-980A-E6D08EE72487

P2860

Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis.

http://www.wikidata.org/entity/Q30442993

description

2007 nî lūn-bûn

@nan

2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Matrix-specific p21-activated ...... permeability in atherogenesis.

@ast

Matrix-specific p21-activated ...... permeability in atherogenesis.

@en

type

label

Matrix-specific p21-activated ...... permeability in atherogenesis.

@ast

Matrix-specific p21-activated ...... permeability in atherogenesis.

@en

prefLabel

Matrix-specific p21-activated ...... permeability in atherogenesis.

@ast

Matrix-specific p21-activated ...... permeability in atherogenesis.

@en

P1433

Q30442993-8D1B9874-167A-4DDE-9742-6346F9681576

P1476

Q30442993-4B3A4644-D486-4113-B12E-377E06A0190E

P2093

Q30442993-0DFB17B5-E13E-4D81-B3F0-4D8DB3B416B3

Q30442993-3B6AACF5-4C62-46B8-885B-1E1D6C90BF6C

Q30442993-99657C3C-98A1-485C-A7A0-F742F4750D24

Q30442993-C0F3339F-B926-40A4-A5C8-EA9D4FAFF31E

Q30442993-DBF61FF6-2011-405D-993B-C28B959F1760

Q30442993-E6C38C5A-9DE9-415E-B50F-8F09F096BD26

P2860

Q30442993-017E5755-0870-4C86-92F2-5419ADFC8AEC

Q30442993-0226AEA9-56FB-4900-8FF6-87458CA215F3

Q30442993-0654415D-9493-4275-AA62-10EB5E57BC2B

Q30442993-06F6AC3B-4540-49EA-ACDE-694373EBA2BB

Q30442993-0DE2997A-6F49-487B-8240-CF57415255CE

Q30442993-1280FB52-1F1C-4C9A-93E2-59247B23E6F0

Q30442993-1509FC61-0772-4BD8-B12E-65A3B65E9DA8

Q30442993-1B20D854-E27A-4E39-9F8A-049955A11829

Q30442993-25F29A1A-9EE7-49B0-AD33-C71F1D8E6D00

Q30442993-3357F61D-18A9-449D-81F9-50AF564E4FFA

P304

Q30442993-EC77BC0F-4071-4659-A833-B9593F224889

P31

Q30442993-55EA7456-E296-41AE-A117-BC2760476182

P356

Q30442993-C3216FA7-491D-44A1-AA20-2555B184922E

P407

Q30442993-BA59389F-9607-442A-9FC7-A9366821E43F

P433

Q30442993-C81C3266-4568-4626-BF03-DBD7B5E0934A

P478

Q30442993-7C4D5EB1-B20A-4E79-86F0-CC44E5432960

P50

Q30442993-CABBDEFE-2960-455E-8037-F1A342458BB3

P577

Q30442993-395E429E-13D1-43FF-9221-903B45143FF6

P5875

Q30442993-2B3BC636-AAC6-480A-AA00-0413546F1BC6

P698

Q30442993-6205E65D-C361-4EAB-9AE2-54C0A054678A

P932

Q30442993-18F83817-191F-4E8C-97F5-8FE3F3630554

P356

P1433

Journal of Cell Biology

P1476

Matrix-specific p21-activated ...... permeability in atherogenesis

@en

P2093

A Wayne Orr

http://www.w3.org/2001/XMLSchema#string

Brett R Blackman

http://www.w3.org/2001/XMLSchema#string

Ian J Sarembock

http://www.w3.org/2001/XMLSchema#string

John M Sanders

http://www.w3.org/2001/XMLSchema#string

Michael B Simmers

http://www.w3.org/2001/XMLSchema#string

Rebecca Stockton

http://www.w3.org/2001/XMLSchema#string

P2860

The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family

Regulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

Atherosclerosis — An Inflammatory Disease

Rho GTPases: biochemistry and biology

VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin

The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity

Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation

Akt phosphorylation of serine 21 on Pak1 modulates Nck binding and cell migration

Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment

P304

719-727

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1083/JCB.200609008

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

176

http://www.w3.org/2001/XMLSchema#string

P50

Martin A Schwartz

P577

2007-02-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6493750

http://www.w3.org/2001/XMLSchema#string

P698

17312022

http://www.w3.org/2001/XMLSchema#string

P932

2064028

http://www.w3.org/2001/XMLSchema#string