Contrasting membrane localization and behavior of halogenated cyclobutanes that follow or violate the Meyer-Overton hypothesis of general anesthetic potency.
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Breaking the Meyer-Overton rule: predicted effects of varying stiffness and interfacial activity on the intrinsic potency of anesthetics.Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptorsProtein kinase C co-expression and the effects of halothane on rat skeletal muscle sodium channels.Effects of volatile anesthetic on channel structure of gramicidin A.Structural consequences of anesthetic and nonimmobilizer interaction with gramicidin A channels.Effects of anesthetics on the structure of a phospholipid bilayer: molecular dynamics investigation of halothane in the hydrated liquid crystal phase of dipalmitoylphosphatidylcholine.Distribution of halothane in a dipalmitoylphosphatidylcholine bilayer from molecular dynamics calculations.Isovaleric, methylmalonic, and propionic acid decrease anesthetic EC50 in tadpoles, modulate glycine receptor function, and interact with the lipid 1,2-dipalmitoyl-Sn-glycero-3-phosphocholine.Distinctly different interactions of anesthetic and nonimmobilizer with transmembrane channel peptides.Membrane structural perturbations caused by anesthetics and nonimmobilizers: a molecular dynamics investigation.Concentration effects of volatile anesthetics on the properties of model membranes: a coarse-grain approachMolecular dynamics simulations of C2F6 effects on gramicidin A: implications of the mechanisms of general anesthesia.Partitioning of anesthetics into a lipid bilayer and their interaction with membrane-bound peptide bundles2-Aminoethoxydiphenyl borate as a common activator of TRPV1, TRPV2, and TRPV3 channelsAnesthetic-like modulation of receptor function by surfactants: a test of the interfacial theory of anesthesiaModeling kinetics of subcellular disposition of chemicals.Alteration of interleaflet coupling due to compounds displaying rapid translocation in lipid membranes.Solute modulation of conformational equilibria in intrinsic membrane proteins: apparent "cooperativity" without binding.Molecular dynamics study of the folding of hydrophobin SC3 at a hydrophilic/hydrophobic interface.Chloroform alters interleaflet coupling in lipid bilayers: an entropic mechanism.Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties.Perflubron attenuates neutrophil adhesion to activated endothelial cells in vitro.In vitro cellular effects of perfluorochemicals correlate with their lipid solubility.Assessing anesthetic activity through modulation of the membrane dipole potential.Analysis of pulmonary surfactant by Fourier transform infrared spectroscopy after exposure to sevoflurane and isofluraneFluorescence anisotropy of diphenylhexatriene and its cationic Trimethylamino derivative in liquid dipalmitoylphosphatidylcholine liposomes: opposing responses to isoflurane.On the mechanism of drug-induced acceleration of phospholipid translocation in the human erythrocyte membrane.Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy.Amino acid volume and hydropathy of a transmembrane site determine glycine and anesthetic sensitivity of glycine receptors.
P2860
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P2860
Contrasting membrane localization and behavior of halogenated cyclobutanes that follow or violate the Meyer-Overton hypothesis of general anesthetic potency.
description
1997 nî lūn-bûn
@nan
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Contrasting membrane localizat ...... of general anesthetic potency.
@ast
Contrasting membrane localizat ...... of general anesthetic potency.
@en
type
label
Contrasting membrane localizat ...... of general anesthetic potency.
@ast
Contrasting membrane localizat ...... of general anesthetic potency.
@en
prefLabel
Contrasting membrane localizat ...... of general anesthetic potency.
@ast
Contrasting membrane localizat ...... of general anesthetic potency.
@en
P2860
P1433
P1476
Contrasting membrane localizat ...... of general anesthetic potency.
@en
P2093
P2860
P304
P356
10.1016/S0006-3495(97)78821-0
P407
P577
1997-04-01T00:00:00Z